514 
PATHOLOGICAL PHYSIOLOGY. 
in pigs, and those will most always develop a pulmonary tuber¬ 
culosis. The lesions may be limited ; yet implanted in the organ- 
ism of the two species of animals thus named, they give rise in j 
both to a manifest tuberculosis. At times, true successive cultures i 
on the guinea-pig are necessary to elevate the virulency to the 
height of the resistance of the rabbit to tuberculization. 
Then the organism of the guinea-pig increases the virulency 
of weakened tuberculous virus, and seems to have no influence 
upon the virus of ganglionar scrofula. 
This fact is quite important, now that there is a tendency to 
consider tuberculosis and scrofula as one and the same disease. 
Once again is shown the difference existing between them. If it i 
is not proved that they are due to different causes, or if it must 
be admitted that they derive from one agent the tuberculous 
bacillus in different degrees of activity, at least it is shown that 
in true ganglionar scrofula this agent is yet further from its 
primitive virulency than in local tuberculosis. Perhaps it is far 
enough from it to form a flxed variety analogous to those micro¬ 
organisms which, after living several generations in an animal 
specie, are in future unable, in spite of all known means, to 
destro} T the spores from whence they came and in which they 
made so many victims .—■Academie des Sciences. 
UPON THE EXHALATION OF CARBONIC ACID IN INFECTIOUS 
DISEASES DUE TO ^EROBIC AND ANAEROBIC MICROBES. 
By M. S. Arloing. 
The connection so justly established lately between patho¬ 
genic micro-organisms and ferments has become the starting 
point of several hypotheses as to the intimate causes of death in 
virulent affections of rapid evolution. 
If the microbe is aerobic, M. Pasteur presents it fighting with 
the red corpuseules, taking the oxygen from which they arc 
loaded, and thus removing from the tissues the necessary element 
of combustion. This phenomena is well shown in the case of 
the bacillus anthracis and of the microbe of chicken cholera. If 
the microbe is anaerobic and acts as such in the organism that is 
