PHYSIOLOGICAL PATHOLOGY. 
515 
producing evident fermentation, the changes are different, as in 
tins case the pathogenic agent is disturbed by the oxygen in the 
manifestation of its properties. 
. Admittin S for au ' ns t a nt that these characters, observed in 
vitro, take place in living media, important differences must be 
met, to the point of view of the intensity of respiratory combus¬ 
tion in the two animals, which succumb, one to the inoculation 
ot an aerobic or to the introduction of an anaerobic microbe. If 
these differences do not exist, the influence deriving from gaseous 
affinities of aerobic bacilli is not primordial in the question pres¬ 
ent. And then, the study of respiration, during the entire dura¬ 
tion of some virulent diseases whose germs belong to the two 
above-mentioned types, offers considerable interest. 
The diseases chosen for this study are affections met in human 
species, viz., malignant pustule and gaseous or foudroyante septi- 
The guinea-pig and the white rat are the animals which were 
used. The greatest part of oxygen consummated and eliminated 
as carbonic acid was dosed during respiration, before the inocula¬ 
tion and during the disease artificially produced. To do this, the 
animals were enclosed before and after inoculation in a peculiar 
apparatus. 
From a large number of experiments made the following re¬ 
sults were obtained : 
First. In anthrax and gaseous or gangrenous septicaemia the 
quantity of carbonic acid thrown out by respiration diminishes 
during the course of the disease, especially towards the last hours. 
Second. This change seems to have shown itself after the 
first effects of inoculation in anthrax, while that after inoculation 
°f gangrenous septicaemia a slight increase in the quantity of ex¬ 
haled carbonic acid was observed for several hours .—Academic 
ies Sciences. 
Cerebro- S pinal Meningitis.— It is stated that Dr. Stalker, 
state Veterinarian for Iowa, on examination of the herd of cattle 
n Guthrie County, of which qnite a number have died, as an- 
lounced in our last issue, pronounced the disease to be cerebro¬ 
spinal meningitis .—National Live Stock Journal. 
