ANALYSIS OF CONTINENTAL JOURNALS. 435 
in a far-advanced period, the scabs being black and dry. As 
to the origin of this eruption, no information could be ob¬ 
tained, as the cow had been but recently purchased. Another 
cow, older in the establishment, and in the same shed, was 
examined by M. Depaul, and was similarly affected, but also in 
an advanced stage; however, the scabs being not quite so drv 
as in the former case, and consequently of a less advanced 
period, were carefully and separately removed from both 
cows and taken to Paris. On removing one of the scabs 
there oozed from the exposed surface a small quantity of 
serum, which was collected in a capillary tube ; some of it was 
also received on glasses (plaques). The scabs and the serum 
were tried on December the 3rd, at the Academy, on a heifer 
(No. 37) without effect. On the other hand, M. Reynal, to 
whom M. Depaul had given two of the scabs from the second 
cow and two of the glasses charged with the serum, made 
the following experiment at Alfort on the 4th of December. 
The scabs were softened in a drop of cold water. With this 
dilution he inoculated a cow on the teats and the labia of 
the vulva; eight punctures were made. On the eighth 
day he ascertained the development of the first pustule. 
On the eleventh day two more appeared, which were re¬ 
markably well developed. He then inoculated another cow 
with the lymph taken from these pustules; this inocu¬ 
lation followed the usual course. From one of the pustules 
of this second generation he filled a tube vTith the lyjnph, 
which was sent to the Academy for the purpose of new 
experiments, but it was lost and nothing more could be done. 
We thus could have surely renewed the cow-pox, but the 
time fixed for the experiments had nearly expired; we there¬ 
fore continued to proceed with that of Beaugency. 
Admitting that the origin of the cow-pox cannot be con¬ 
tested, some have asked the question whether it would be 
possible to pass the lymph from heifer to heifer, and thus 
keep up the source and supply the wants of vaccination ? 
What the commission has done during the space of more 
than eight months is an affirmative answer to that question. 
With a little care it is easy to obtain the same results. Four 
heifers were successively inoculated with the cow-pox virus 
obtained from Naples, forty-two with that of Beaugency, 
and in all these cases nothing has marred the progress of the 
researches. Different modes of inoculation were employed, 
viz. by incision, puncture, either with the lancet or the 
needle, and the pustules have always been equal to the 
number of inoculations, varying from forty to eighty. The 
incisions were given up early, for the sole reason that they 
XLIl. 31 
