438 
ANALYSIS OF CONTINENTAL JOURNALS. 
their private use, and which was not a small quantity. It did 
not suffice Monsieur le Ministre to be convinced as to the con¬ 
servation of the vaccine bv transmission from heifer to heifer, 
and thereby show that it was possible to establish a service 
of vaccination, and, further, that each individual animal was 
capable of furnishing a considerable amount of lymph for 
the purpose of inoculation (vaccination) ; it was also neces¬ 
sary to show that this new process of vaccination w'ould be a 
safeguard against the inoculation syphilitic virus. 
V'accination has, it can no longer be denied, already pro¬ 
duced some cases of syphilitic infection, though they are not 
very numerous in proportion to the great number of vaccina¬ 
tions made every year, but we can no longer overlook the 
possibility of similar accidents, and it is the duty of the 
medical faculty to prevent it by all the means in their power. 
All efforts made up to the present time have not tended to 
avert the danger. 
Would animal vaccination have this advantage ? No doubt, 
if it were demonstrated that the bovine species are inaccessible 
to syphilis. A great number of experiments already made— 
although with otlier objects in view—seem to have estab¬ 
lished the fact that syphilis is not transmissible to animals, 
ffliat is the general opinion, which is founded on the authority 
of Hunter and the followers of his doctrines, but this has 
been contradicted by some concerning animals not of the 
bovine species; the commission has, therefore, deemed it 
necessary to make some experiments on the latter in order 
to decide this important question. 
Inoculation of a heifer with syphilitic virus. 
Eivp. 1.—To obtain the syphilitic virus, M. Depaul went 
to the venereal hospital in company with M. Sirnounet, the 
doctor of the establishment. He selected a patient under 
the following conditions:—Age 24, entered the hospital 19 th of 
June, was infected three weeks before admittance. The first 
signs of the infection were two small pimples at the base of 
the glans penis and the prepuce; soon after, ulceration 
was established on both. On examination we found two 
ulcers, one on the gland the other on the prepuce, the latter 
more extensive than the former, having the dimensions of a 
piece of 50 centimes; both had prominent bases and an in¬ 
durated rim ; discharged a sanguineous purulent matter. 
Besides this the inguinal ganglia were enlarged ; there were 
no manifestations of secondary symptoms. 
