439 
ANALYSIS OF CONTINENTAL JOURNALS. 
No specific treatment had been adopted. M. Depaul had 
this patient brought to the Academy on the ^23rd of June. 
He made, in concert with M. Blot, the following experiment 
on the heifer which had brought the cow-pox to Paris (No. 
1 of the second series). He made six inoculations in the 
right mammary region, which had been previously shaved. 
Three were made with the ordinary vaccinating lancet, and 
the three others by incision in the skin; for the first the 
lancet was dipped each time in the pus of two of the chancres 
(syphilitic sores), and were well loaded with pus; for the 
second, after having made the superficial incision in the skin, 
removed and dried the small quantity of blood from the 
wound, the syphilitic virus from the sores was introduced 
into the gaping wound ; besides this two more punctured 
inoculations were made at the internal surface of the right 
ear. After the operation the animal was reconducted to the 
stable and carefully watched; the inoculated parts speedily 
dried, without showing the slightest sign whatever of inflam¬ 
mation. No other manifestations were observed; the animal 
remained in perfect health up to the 4th of August, when it 
was submitted to another experiment of the same kind. 
Exp. 2. —'I'his time the pus was taken from the sores of 
two patients selected from the venereal hospital b}^ M. Ricord, 
and the inoculation was made, on the 4th of August, by M. 
Depaul, in the presence of MM. Ricord, Blot, and Jac^ue- 
mier. The history of the patient is as follows :—F. G—, 
aged 25, entered the hospital August 1st; the infection was 
of nineteen days^ standing; the commission ascertained the 
})resence of an ulcer, the size of a 20-centimes piece, in the 
prepucial groove on the left side, which had the characteristic 
induration, secreting a sero-sanguineous pus of a yellowdsh 
colour, not very abundant. There were a great number of 
enlarged indolent ganglia in the left inguinal region, and 
some also, but not so large, in the right. The patient 
had not been submitted to any special treatment. Four 
inoculations were made with the virus from this patient, 
the same precautions being taken in this as in the former 
case. 
The second patient, A. J—, aged 20, entered the hospital 
on 28th of Jul}"; the infection, dated from four weeks pre¬ 
vious; the chancre or sore had invaded the whole of the 
glando-prepucial groove ; induration at base, salient surface, 
ulcerated fungoid, &c.; sero-{)urulent suppuration rather 
abundant; no secondary symptoms. With the virus from 
this patient four fresh inoculations were made on the same 
heifer, at a certain distance from the first, two by puncture 
