44 ACTION OF SALCYLIC ACID AND THE SALICYLATES. 
rapid rise in temperature; but these symptoms soon sub¬ 
sided, and were replaced by a great improvement in the 
general condition of the patient. 6. He would not limit 
lacteal injection to cases in which profuse and exhausting 
haemorrhage had occurred, but recommended their use in 
certain cases of typhoid fever, pneumonia, cholera, &c.— 
British Medical Journal . 
FOWLER’S SOLUTION. 
It has been discovered by Rouyer that freshly pre¬ 
cipitated sesquihydrate of iron, although an antidote 
for arsenious acid (arsenic of the shops), fails entirely to 
counteract the action of the arseniate or arsenite of potassa 
(Fowler's solution), but that a mixture of a solution of the 
sesqui-chloride of iron and the oxide of magnesium will 
counteract the effect of these salts, as well as the arsenious 
acid itself, and hence this mixture is always to be preferred 
to the hydrate in cases of poisoning by arsenic. The officinal 
solution of the sesqui-chloride of iron should first be adminis¬ 
tered, and afterwards the magnesia. In one hour after the 
administration of the antidote, a cathartic should be given. 
In all cases acid drinks (such as lemonade) are to be avoided, 
since the compounds they form are soluble .—The Chemist and 
Druggist. 
ACTION OF SALICYLIC ACIDS AND THE SALICYLATES. 
Chrorie and Petrucci have made a series of experiments on 
these remedies, and have arrived at the following conclusions ; 
—Both salicylic acid and the salicylates have the same biolo¬ 
gical action, but with the first local, with the latter general 
conditions are of most importance. Salicylic acid, both free 
and as a salt, lowers, in small doses, the temperature, though 
not to any extent. In large doses it not only does not depress 
it, but it actually augments it to a very marked extent. 
Animals submitted to the daily consumption of the acid or 
of its salts, become rapidly thinner, and lose weight. The 
beats of the heart in the frog are increased in frequency, after 
the use of salicylate of soda, but in animals they are sometimes 
