SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. 329 
2. How do they obtain entry into the systems of infected 
animals ? These are the questions into the solution of which 
the matter resolves, and which ought to be investigated. 
The second is most urgent, and its answer should elucidate 
the first; for if it be shown that the Bacteria enter in such or 
such a way, a limit will be thus given to examine for their 
presence in substances related to such way of introduction— 
food, drink, or air. To direct these practical researches 
assistance was derived from those made in the laboratory, 
which have enabled M. Toussaint to trace the course of 
Bacteria after inoculations by means of the lesions they pro¬ 
duce in organs. In a note communicated to the Academy of 
Sciences, 3rd June, 1878, he says that “ the results which I 
have established enable me to determine in what part of the 
economy, and by what mode of entry the parasites introduce 
themselves.” One of his colleagues inoculated a sheep 
which M. Toussaint examined after death, and he was 
enabled to determine the part inoculated, though it bore no 
trace of lesion. These premises with regard to the determi¬ 
nation of the way of introduction being settled, M. Toussaint 
in his memoire describes the phenomena resulting from 
inoculation from the period of incubation until death. He 
notes the multiplication of the Bacteria in the subcutaneous 
cellular tissue, the irritation which their presence causes, 
the serous exudation which results, and which is a medium 
favorable for their germination ; finally, their localisation for 
a certain time. Then their passage through the lymphatics, 
the irritant action which they exert on neighbouring glands, 
resulting in the complete obliteration of their structure, and 
after that their passage into the blood. M. Toussaint, from 
his researches, attributes a very marked inflammation pro¬ 
ducing a tendency to Bacterids, which is more or less marked 
according to the organisms invaded, being very active in the 
dog, horse, and ass, less so in the sheep and rabbit. This 
phylologenous tendency determines rupture of the capil¬ 
laries at various points, and causes symptoms of very intense 
pain. These ruptures give rise to deep-seated, true inocula¬ 
tions, which are related to the lymphatic glands in the same 
way as experimental inoculations. In the rabbit and sheep 
since the inflammatory action of Bacteria is but little marked, 
after death they are found only in the blood-vessels, “ and in 
those glands alone which are situated on the course of the 
lymph vessels coming from the point of inoculation.” These 
well-marked experimental results give M. Toussaint the 
one by means of which he has been enabled to ascertain in 
animals which have recently died from charbon, or better, 
