380 FIBRO-VASCULAR TUMOUR IN THE BLADDER. 
that time her appetite had been good. He found her ex¬ 
hibiting the following symptoms: pulse very feeble and 
quick, mucous membranes blanched, appetite lost, eyes 
sunken, and breathing accelerated. At times she would 
stretch herself as if in pain; she was also very much ema¬ 
ciated. My pupil prescribed two doses of tonic laxative 
medicine, and ordered plenty of gruel to be given her. 
22nd March.—On visiting the animal to-day, I found 
that the symptoms were much aggravated. She is now 
nearly pulseless, and in addition her back is arched, and she 
is almost constantly straining and passing a small quantity— 
fifteen or twenty drops—of pale, blood-coloured urine, which 
stains the straw as it falls. Her breath is foetid; respi¬ 
ration is accompanied with a grunt, and she is so feeble as 
scarcely to be able to stand. From the hopeless state of 
the case, I ordered her to be slaughtered.— Diagnosis, chronic 
disease of the bladder. 
March 23.—Autopsy. On opening the chest I found the 
lungs emphysematous and much enlarged, with here and 
there deep-seated spots of sub-acute inflammation. The 
right lung was adherent to the ribs. On opening the abdo¬ 
men the liver was found to be pale, hard, and tough, with 
here and there large, irregular patches of a dirty yellow 
colour, even harder and tougher than the other portions of 
the organ. The bladder was enormously diseased and dis¬ 
tended with urine, and fearing it might rupture and thus 
cause the loss of the fluid, I punctured the fundus, as you 
will perceive, in order to send you some of its contents. 
There is, you will discover, an enormous substance near 
the neck of the bladder, at its inferior portion, from the inner 
surface of which the blood, I conceive, must have escaped. 
It appears to me, from the imperfect glimpse I could get from 
the hole in the fundus, that the tumour was coated with a 
thin layer of calcareous deposit. For fear of lessening, how¬ 
ever, your interest in this somewhat unusual specimen of 
disease, I have not cut into the bladder, and am therefore not 
in a position to do more than hazard an opinion that the 
tumour may prove to be of a cancerous nature. The fluid 
sent represents rather the sediment of the urine, so to speak, 
than that which was voided when the animal was alive, which 
at that period was of a sero-sanguineous character. 
I am, &c.. 
To Professor Varnell. 
On receipt of the above letter, I wrote to Mr. Kettle to 
ask him if he could get any additional information in re- 
