TRANSLATIONS FROM CONTINENTAL JOURNALS. 849 
limping, and then fell down. The wounds extended and 
assumed an unhealthy aspect; the right hind leg became 
tumefied; the typhoid state persisted; gangrene set in, 
and the dog died ten days after the second injection. 
Autopsy. — Lungs, heart, and liver normal; the mucous 
membrane of the stomach presented a vivid red colour 
towards the pylorus ; that of the duodenum showed some 
traces of inflammation, and also some small ulcerations, the 
largest of which was about a centimetre in circumference, 
and was situated near to the pylorus; they affected the 
intestine even to the peritoneum, which at that place pre¬ 
sented a violet colour. The colon contained soft ingesta of a 
dark-red colour, and presented a great many slate-coloured 
spots, some of which showed traces of suppuration in their 
centre. The difference in the results of the experiments 
practised on these two dogs cannot be more evident, and 
cannot be explained otherwise than by attributing to the sul¬ 
phite taken by the first subject, before the injection, an 
antiseptic effect which neutralized the effect of the purulent 
ferment, while in the other it developed its morbid effect 
without any obstacle, and to "which he fell a sacrifice. To 
remove all doubts on the results of this experiment, M. Polli 
wished to make a counter proof that the strength of the dog 
who fell a sacrifice to the injection of the pus was greater 
than the one "which resisted the effect after having been 
treated with the sulphite. This w’as of great value, but he 
wished still further to eliminate the influence depending on 
the individual resistance of the inoculated animal, so as to 
attribute to the remedy neither more nor less than that 
which absolutely belonged to it. The same dog which 
had, thanks to the protective influence of the sulphite, 
so well resisted the injection of the pus, continued to 
be in perfect health, was submitted to the following ex¬ 
periment five days after' leaving off the sulphite; another 
injection of one gramme of pus was made, and this was 
repeated two days after, without, however, the administra¬ 
tion of the sulphite during the interval. A few minutes 
after the first injection the dog seemed prostrated, he vomited 
and had several evacuations, was dull, and remained lying 
down the whole of that day. The next day he had recovered 
a little of his vivacity; but immediately after the second in¬ 
jection he was greatly prostrated, and remained down the 
whole of the day ; the following day he was able to take 
a little food; the day after, having remained prostrated 
in his kennel and taken very little food, but drank a 
great deal, he walked with great difficulty and limped; the 
