850 TRANSLATIONS FROM CONTINENTAL JOURNALS. 
wounds where the inoculation had been made became en¬ 
larged, and had a bloody, fetid discharge. At the end of six 
days the dog presented all the symptoms of typhoid fever; 
he began to recover a little, that is to say, after another six 
days he regained his strength and appetite, the wounds began 
to cicatrize, so that, twelve days after the last injection, he 
might be considered convalescent. The dog was now killed by 
a blow on the head with a hammer. At the autopsy traces 
of old inflammation were found in the intestines, such as 
injection of the mucous membrane of the duodenum and 
vascular arborisation on the whole of the small intestines. 
If in this second experiment the dog had died like the 
others the conclusion in favour of the prophylactic and the¬ 
rapeutic virtue of the sulphite would have been certainly 
more evident; but nevertheless it does not fail to give us an 
important proof of the efficiency of the remedy, inasmuch as 
in the first experiment the artificial poisoning of the blood 
produced only a slight indisposition, and, on the contrary, 
provoked a grave malady in the same animal when not under 
the prophylactic influence of the sulphite. The experiment 
confirms the necessity pointed out above, of always taking into 
consideration the peculiar impressibility of the individual ope¬ 
rated on, so as to avoid the possibility of erroneous conclusions. 
Experiment with putrefied hlood .—To a greyhound, weigh¬ 
ing eight kil., sixteen grammes of the hyposulphite of 
soda were given in two days, in one-gramme doses. On 
the 9th of March, 1861, at 3 p.m., two hours after the 
administration of the last dose, three grammes of blood in a 
state of putrefaction were injected into the femoral vein of 
the right leg. The blood used in the five comparative expe¬ 
riments which follow 7 was always the same; it was blood of 
an ox clefibrinated and exposed to the air for a month 
(November), and was quite putrid; it was afterwards pre¬ 
served during three months in a bottle corked up. It w r as of 
a red-violet colour, extremely fetid, and of an ammonial 
odour; by the microscope some red corpuscles, fringed or 
starred, as described by Richardson in ammoniacal blood, 
were discovered. A few minutes after the injection the dog 
vomited some mucous matter mixed with blood; aftenvards 
some whitish viscous matter; faecal evacuations also occurred 
at the same time. Some balls in which the last doses of 
the hyposulphite were incorporated were next administered. 
After this the dog did not seem so much distressed; he 
remained seated in the usual way on his hind legs. On 
taking him to his kennel he ran into it with alacrity, and 
without limping. However, during the rest of the day he 
