152 SYNOPSIS OF CONTINENTAL VETERINARY JOURNALS. 
equally large opening externally. The canula was intro¬ 
duced, without difficulty, into the jugular or other large 
vein, escape of blood through the needle serving to indicate 
that it had penetrated the vessel. This syringe is very 
useful for intra-venous injection of remedial agents, for which 
use Dr. Moller had it constructed. He considers it has great 
advantages over other methods proposed for the same pur¬ 
pose, and especially notices that Helper’s apparatus is rather 
difficult to use in practice. In all cases, shortly after the 
transfusion of tetanic blood, the animal experimented upon 
exhibited a very marked rise in temperature, accompanied by 
violent muscular twitchings in all parts of the body. When 
the case of tetanus was a chronic one—that is to say unac¬ 
companied by fever—the elevation of temperature was more 
gradual, less marked, and less persistent than when the 
tetanus was acute and accompanied by fever. In the former 
the elevation of temperature, on an average, was 2° or 3° C. 
at the end of seven or eight hours, and twenty-four hours 
after the operation the body had regained its normal tem¬ 
perature. Two horses before the operation gave readings of 
§8*8° and 38’4°; after receiving the blood of a patient suffering 
from acute tetanus in half an hour these had risen to 40*2° 
and 40T° respectively; the maximum readings (41° and 4T2°) 
were attained after five or six hours, and the normal resumed 
only after forty-eight hours. It is as well to note that the 
former of these animals, before transfusion, had an amount 
of blood equal to that injected removed by bleeding. This 
precaution was not adopted with the other. Also, in neither 
of the cases was there any extension of the first symptoms, 
showing a true tetanus. The same syringe was used for 
injection of chloral hydrate into the veins of tetanic horses, 
but the results were generally unsatisfactory. With doses 
of 100 to 125 grammes relaxation of the muscles almost in¬ 
variably occurred, but after a state of narcotism, which 
lasted about four or five hours, the spasms again appeared, 
often with increased intensity, and the animals, falling 
down, were generally most violently agitated. On the other 
hand, chloral hydrate given en lavement gave good results, 
as seems from the observations of M. G. Hartmannn 
(Monatschrift des f. Ver der Th. in Oesterreich, I, No. 4) on 
two cases of cure by this method, after persistence for 
twenty-one days in one case and fourteen in the other, the 
agent being given in daily doses of from three to twenty- 
four grammes (about 3ij—3vj) in 500 to 1500 grammes of 
water, and administered many times ( Archiv f. Wiss. und 
Prakt. Thierheilhunde). 
