458 SYNOPSIS OF VETERINARY CONTINENTAL JOURNALS. 
February, 1875, a case presented itself, a heifer exhibiting 
all the signs of charbon. The disease had already lasted 
six hours. Intravenous injection apparatus not being to 
hand, M. Jolly endeavoured to introduce a solution of iodine 
into the jugular by means of a small funnel, but this became 
blocked up by clots, so at last it was determined to admi¬ 
nister the iodine solution in drench. Immediately after 
administration the animal fell as if thunderstruck, and was 
expected to die every moment, until at the end of an hour 
her distress ceased. She got up and returned to her stable. 
A second dose (less by one half) having been given hex- 
similar but less intense effects followed. That evening the 
state of the hei f er was much improved. The following 
morning she was lively, active, and greedily devoured her 
food; and, having been separated from the rest, bellowed 
constantly, and made efforts to break her fastenings and 
return to her original quarters. This did not last. On the 
afternoon of this day of apparent convalescence the heifer 
died, in spite of the administration of another dose, which 
was followed by effects similar to the others. Autopsy 
showed the presence of false membranes, the result of peri¬ 
tonitis, besides the ordinary lesions of charbon. In 1876 
the disease again broke out in the same place; an empirical 
remedy which had proved successful in one case, and gene¬ 
rally caused a temporary remittence of symptoms, was tried 
in association with iodine preparations administered by the 
mouth. (This remedy consisted of vinegar, salt, and mus¬ 
tard.) This outbreak caused the loss of twenty-one animals. 
Then M. Jolly obtained the apparatus of Dieulafoy for intra¬ 
venous injection. The disease again appeared in 1877. 
When M. Jolly was called in six cows were affected ; of these 
three were just dead, and two were in articulo mortis . On 
these latter he tried the intravenous injection of ten grammes 
of solution of iodine in ten grammes of warm water. This 
was done as an experiment, for the state of the animals gave 
no opportunity of benefit. A slight temporary amendment 
followed the operation, but the next day the animals died. 
But in another stable on the same farm eight affected ani¬ 
mals, treated by means of intravenous injection of iodine and 
administration of the same agent in drench, recovered. A 
cow in calf, from a third stable, having been violently 
attacked by the same disorder, the farmer and proprietor, 
with whom M. Jolly had left full directions, resolved to try 
injection of iodine by the jugular. They gave larger doses 
than had been administered to the other animals, and iodine 
also was given in drink. The success was complete, the 
