VACCINE AND CALF VACCINATION. 
399 
I feel that what I have been able to report is very meagre, 
and I only wish it had been in my power to send you a better 
and practically a more useful description of the disease. 
I am, &c., 
W. S. Wallis. 
Experiments. 
Vaccination of a Calf with the reputed Primary Vaccine 
Lymph. 
July 2nd.—A well-bred, healthy, red-and-white male calf, 
about fourteen weeks, was vaccinated at the Royal Veteri¬ 
nary College with the Halstead lymph. The place selected 
was the under part of the abdomen in front of the scrotum, 
where the skin was very thin and white in colour, being de¬ 
void of pigment. Previously to the punctures being made 
the hair was removed by shaving, so as to leave the part 
perfectly nude, that the effects of the vaccination might be 
more closely and satisfactorily observed. Twelve punctures 
were made, from half to three fourths of an inch apart, 
and four sets of scratches. Fully half an hour was occu¬ 
pied in the vaccination, and the quantity of lymph employed 
was large, not less than three well-charged points being used 
in each of the punctures, with a corresponding quantity on 
each set of scratches. 
The animal was examined day by day, and with the ex¬ 
ception of a little diffused redness, which on the day follow¬ 
ing the vaccination was present on the part generally, but 
chiefly on the site of the punctures and scratches, no effects 
whatever ivere produced. One puncture, on the third day 
looked as if a bulla might form ; such, however, did not 
take place. 
On the sixth day, of the vaccination the failure of the 
experiment was forwarded to Dr. Buchanan and Mr. Ceely. 
Vaccination of the Human Subject. 
On July 9th Dr. Buchanan, in acknowledging the receipt 
of the report, stated that some experiments were being made 
on the human subject by the lymph; and on July 11th Mr. 
Ceely wrote as follows : 
Aylesbury. 
My dear Sir,— Many thanks for your obliging, note and 
especially for the care and pains you have taken with the 
reputed “ primary vaccine.” 
I fully expected that the result of the insertion of the points 
would prove the spurious character of the eruption. 1 he utmost 
that I looked for was the reproduction of the vesicle or bulla 
