166 
Journal of Agricultural Research voi. xxiii, No. 3 
The drug apparently was entirely ineffective in removing hairworms 
of the genus Capillaria in cases where it was given in single doses of i or 
2 cc. per kilo, but the failure to find these worms post mortem in the five 
birds given large and repeated doses suggests that these doses may have 
killed the worms although the dead worms were not found in the feces, 
owing to their small size and the difficulty of finding them. 
As regards the efficacy of the drug against Ascaridia per spirillum, it 
failed to remove any of these worms from one bird when given at the rate 
of i cc. per kilo but removed all the worms present in three cases when 
given at the rate of 2, 4, and 5 cc. per kilo. 
As regards its efficacy against Heterakis papillosa , carbon tetrachlorid 
in doses of 1 or 2 cc. per kilo failed to remove any of a total of 25 worms 
present in three birds. In another case the drug, at a dose rate of 1 cc. per 
kilo, removed 34 of 40 worms present, or 85 per cent. In the case of the 
five birds given large and repeated doses, no worms were found post 
mortem, this fact suggesting that some worms may have been removed al¬ 
though not found in the droppings. These findings suggest that the drug 
may be effective when it actually enters the ceca and gets in contact with the 
worms present. They also suggest that the entrance of the drug might 
be insured by the use of large or of repeated doses. This would appear 
to be feasible in conditions where the presence of these worms warranted 
it, inasmuch as the drug appears to be quite safe and well tolerated in 
large doses. 
The drug was quite ineffective against tapeworms in chickens, as in 
other animals. 
An additional test of the effect of carbon tetrachlorid on chickens 
(Rhode Island Reds) was conducted as follows: 16 chickens, of which 8 
were 1 year old and 8 were 2 years old, weighing on an average about 5 
pounds each, were each given 1.5 fluid drams, about 5.5 cc., of carbon tetra¬ 
chlorid by catheter to the crop, the birds not being fasted. The dose rate 
was about 2.27 cc. per kilo. The egg production for the 10 days previous 
to treatment averaged 9.6 eggs a day; for the day of treatment, May 14, 
it averaged 8 eggs; and for the 10 days following treatment, it averaged 
10.8 eggs a day. It is evident from these results that the treatment had 
no deleterious effect on egg production. On the other hand, it could 
not be assumed from one test on 16 chickens that the increase in egg 
production, amounting to 1.2 eggs a day, was correlated with the admin¬ 
istration of carbon tetrachlorid. 
Hall and Shillinger 3 report some experiments with drugs injected 
by rectum into chickens for the removal of the cecum worm, Heterakis 
papillosa, the drugs used including carbon tetrachlorid. Six chickens, 
weighing about 1.5 pounds each, were injected with this drug. The quan¬ 
tities given and the results obtained in removing H. papillosa are as 
follows: 
No. 14; 10 cc.; passed 79 worms; post mortem, no worms; efficacy, 100 
per cent. 
No. 15; 10 cc.; passed 2 worms; post mortem, no worms; efficacy, 100 
per cent. 
No. 16; 5 cc.; passed 1 worm; post mortem, no worms; efficacy, 100 
per cent. 
3 Hai,l, Maurice C., and Shillinger, Jacob E. the removal of heterakids from the ceca of 
CHICKENS by RECTAL injections OF anthelmintics. In Jour. Amer. Vet. Med. Assoc. (In press.) 
