Table  2,  yet  the  weight  of  red  cells  haemolysed  by  sodium  hydrate  is 
nearly  ten  times  that  haemolysed  by  the  quinine  salt  during  the  same 
period  of  tune  at  the  same  temperature. 
5.  Action  of  quinine,  hydrochloric  acid  and  sodium  hydrate 
on  red^  blood  cells  compared . 
In  the  preceding  observations  the  concentration  of  the  various 
haemolytic  agents  has  been  given  in  percentage  terms.  For  the  sake 
of  comparison  all  these  results  are  grouped  together  in  Table  8. 
The  action  of  these  agents,  if  it  be  of  a  chemical  nature,  will  be  a 
molecular  action,  and  in  this  case  the  concentrations  employed  can  be 
compared  only  if  they  are  expressed  in  molar  form.  In  Table  8, 
therefore,  the  molar  concentration  is  given  by  the  side  of  the 
percentage  concentration,  and  similarly  the  maximum  weight  of  red 
blood  cells  haemolysed  is  given  not  only  in  terms  of  the  absolute 
weight  of  the  haemolytic  agent  present,  taken  as  a  unit,  but  also  in 
terms  of  a  gramme-molecule  of  the  latter,  taken  as  a  unit.  In  this 
fable,  in  addition  to  the  results  already  given  in  the  first  seven 
Tables,  an  additional  concentration  of  sodium  hydrate  at  the  transition 
point  is  also  given,  but  it  has  not  been  thought  necessary  to  give  the 
complete  table  from  which  this  result  has  been  taken,  for  a  further 
series  of  experiments,  with  slightly  lower  concentrations,  is  given  in 
Table  1 1. 
Table  8.  Showing  the  relative  amounts  of  human  red  cells  completely  haemolysed  in 
three  hours  by  quinine  bihydrochloride,  quinine  in  alkaloidal  state, 
hydrochloric  acid  and  sodium  hydrate. 
'Inblc 
Haemolytic 
aj^ent 
Concentration  of 
haemolytic  agent 
Weight  of  wet  red 
cells  :  Weight  of 
haemolytic  agent 
VVet  red  cells  (in 
grammes)  :  Haemo¬ 
lytic  agent 
(gramme-molecule) 
I 
Q.  2  HCl 
0-0450%  =  0-00 1 13  Al 
10*4  :  I 
4130  :  I 
2 
5? 
O' 1^50%  =  0-00389  M 
15-6:1 
6200  :  r 
.1 
Q.  (alkaloid) 
0-6350  %  =  0-01 600  M 
36-4  :  I 
14430  :  I 
5 
0-0628  %  =  0-00198  M 
6*4  :  T 
2070  ;  r 
6 
M  ci 
0*0114%  =  0*00320  M 
182-0  :  1 
6640  :  I 
NnOI  1 
0*0157%  ==  0*00380  M 
0*0090%  =  0*00226  M 
1 66*0  :  1 
133*0  :  1 
6640  :  I 
5320  :  I 
