75 
at  which  the  patient  passed  urine,  this  did  not  become  evident.  'Much 
variation,  it  may  be  observed,  was  exhibited  in  respect  of  the  passage 
of  urine,  in  some  attacks  urine  being  passed  frequently,  in  others 
retained  long  in  the  bladder.  Failure  to  observe  haemoglobinaemia— 
assuming  for  the  moment  that  this  is  constantly  present  during 
haemoglobinuria,  a  point  which  will  be  further  considered  on  pp. 
86  to  8g— would,  therefore,  be  expected  to  occur  in  a  certain 
proportion  of  the  cases  examined  during  the  passage  of  urine 
containing  haemoglobin. 
■rAT)i.E  34  Examination  of  blood  plasma  for  the  presence  of  dissolved  haemoglobin, 
during  haemoglobinuria  of  blackwater  fever.  Selected  from  Table  33. 
No.  of 
obser¬ 
vation 
Case 
Percent¬ 
age  of 
haemo¬ 
globin 
in  plasma 
Condition  of  urine  at  time  of  collecting  plasma. 
3 
16 
19 
22 
25 
32 
2 
7 
8 
ro 
1 1 
i+a 
o-'3% 
0-13% 
°-i3% 
O’og  % 
0-25  % 
0-20% 
On  centrifugalising  the  urine  the  supernatant  liquid  was  found  to  be 
brown  in  colour,  gave  no  oxyhacraoglobin  hands,  but  yielded 
jig  col.  of  brown  precipitate  on  boiling  after  acidification  with 
acetic  acid  (=  about  0-2%  of  haemoglobin). 
Similar  to  above 
Urine  contained  o-t  %  of  dissolved  haemoglobin.  See  Eig.  12 
))  °'°3  %  >1  11  '  3 
u  °'9  %  ”  ”  ’  + 
u  t)-24%  „  '»  *7 
6 
7 
18 
21 
23 
H 
3° 
33 
34 
36 
37 
3« 
39 
3 
0-57% 
0-40  % 
>5 
7a 
°74  % 
?? 
TO 
% 
0-30% 
if 
0-20  % 
H 
°-57% 
» 
15 
°-56% 
)) 
o-r-  % 
17 
°-^5  % 
)) 
0-67  0/0 
)) 
°-95  % 
5> 
0-48% 
5> 
1-2% 
■•3  % 
0-4%  to  i-i  % 
I  • '  % 
f5% 
0'4% 
>•5% 
'■3% 
°7% 
3-'% 
■•4% 
>■9% 
°-5% 
13 
i1 
V 
)y 
16 
18 
„  20 
n  » 
5>  n 
Further  support  to  this  view  is  afforded  by  Table  34,  in  which 
the  percentages  of  dissolved  haemoglobin  in  the  blood  plasma  in  the 
nineteen  observations  last  referred  to  are  given  side  by  side  with  the 
corresponding  percentages  of  haemoglobin  in  the  urine.  It  will  be 
seen  that,  in  the  cases  (3,  16,  19,  22,  24,  25,  32)  in  which  the  percentage 
