8i 
urine  by  boiling  was  indistinguishable  from  that  obtained  on  boiling 
a  solution  of  haemoglobin.  In  particular,  no  lighter  colour,  such  as 
might  be  taken  to  indicate  the  presence  of  serum  albumin  or  globulin 
could  be  detected,  when  the  former  precipitate  was  compared  with 
the  latter. 
1'able  36.  Examination  of  oxalatccl  blood  plasma  for  the  presence  of  dissolved  haemoglobin, 
in  experimentally  induced  haemoglobinuria  in  rabbits.  Selected  from  Table  3^. 
No.  of 
Experi¬ 
ment 
Percentage  of  haemoglobin  in 
plasma 
Condition  of 
urine 
I 
°'5  % 
Dr 
ess 
Urine 
contained 
trace  of  haemoglobin 
z 
0-8 1  % 
to 
less  than 
O' 49  % 
0-09  % 
11 
3 
5-°4  % 
to 
3-'o% 
51 
i'7°% 
„  See 
4 
6-?o% 
to 
176% 
11 
'•32% 
5 
4-34% 
to 
3-17% 
0-84% 
)• 
,, 
2-45  % 
6 
8-59% 
to 
less  than 
11 
0-63% 
1) 
7 
{“) 
5’'3  % 
to 
2-20  % 
11 
4'8o%) 
(!>) 
9-20% 
to 
less  than 
3'54'’d 
1) 
2' 50  % 
i' 
(d 
8-50% 
or 
more 
,, 
4-50  %  1 
8 
to 
'0'4% 
?1 
7'2o‘’,;, 
>1 
9 
2-20  % 
to 
2 '00% 
„ 
1 1  *20  %  (maximum) 
10 
0-90 
to 
0-54% 
7*00%  (maximum) 
In  Table  36  some  of  the  percentages  of  haemoglobin  in  blood 
plasma  and  urine  are  placed  side  by  side  so  that  the  degree  of 
haemoglobinaemia  and  haemoglobinuria  may  be  compared,  as  was 
done  in  the  case  of  the  blackwater  fever  observations  recorded  in 
Table  34.  The  highest  degree  of  haemoglobinaemia  observed  in 
the  rabbit  is  I0'8  per  cent.,  wTile  the  highest  amount  in  blackwater 
fever  was  0'g5  per  cent.  It  must,  however,  be  observed  that  in  the 
former  case  the  observations  were  frequently  repeated,  and  the  time 
at  which  the  maximum  would  occur  was  known  in  advance,  while  in 
the  human  subject  the  number  of  observations  which  could  be  made 
was  limited  and  the  probable  course  of  the  haemoglobinaemia  was 
unknown,  so  that  highest  percentages  were  therefore  in  all  probability 
not  ascertained. 
In  comparing  the  degree  of  liacmoglobmacmia  with  that  of 
haemoglobinuria  in  experimentall)?  induced  haemoglobinaemia  it 
must  be  remembered  that  the  last  three  experiments  in  Table  36 
stand  apart  from  the  others  since  in  these  the  urine  was  collected 
F 
