log 
compared  with  the  latter.  A  further  characteristic  alteration  in  the 
aspect  of  the  kidney  was  presented  by  tlie  medulla,  which  was  quite 
abnormal,  being  dark  brown  almost  black  in  colour,  especially  at  the 
bases  of  the  pyramids.  On  closer  examination  it  was  seen  that  this 
was  due  to  fine  brown  radiating  lines,  presenting  a  somewhat  fan-like 
character  and  readily  seen  with  the  naked  eye.  Fine  brownish  dots 
could  also  be  recognised,  though  not  so  readily,  scattered  here  and 
-/.-r 
Fig.  34.  Transverse  section  of  medulla  of  kidney  during  suppression  of 
urine,  eight  days  after  haemoglobinuria  had  ceased.  Blackwater 
Fever,  Case  7a.  Many  of  the  large  collecting  tubules,  which  are 
dilated  and  exhibit  flattening  of  the  epithelial  lining,  are  partly 
filled  with  darkly  staining  granular  material.  The  individual 
granules,  which  are  about  5^1  in  diameter,  are  in  some  places  discrete 
but  are  more  frequently  closely  packed  so  as  to  form  irregular  masses. 
In  some  of  the  tubules  also  free  epithelial  cells  are  seen.  The  renal 
epithelium  though  flattened  shows  no  degenerative  changes.  The 
interstitial  tissue  does  not  exhibit  any  cell  infiltration  or  other  marked 
alteration.  No  malarial  pigment  is  recognisable.  Hardened  in 
alcohol.  Stained  with  iron  alum  haematoxylin.  x  130. 
