In  the  interstitial  tissue  of  the  kidney  no  cell  infiltration  or  other 
change  was  present.  The  blood  vessels  of  the  kidney  were  usually 
empty.  No  malarial  pigment  was  found  in  the  blood  vessels  or 
elsewhere.  No  haemorrhages  were  seen  in  the  interstitial  tissue  of 
;S;'Lr’ 
-wOv 
I - 
/JOJU 
— I 
300  JU 
Fig.  41.  Section  o£  cortex  of  kidney,  seven  days  after  haeraoglobinuria 
had  ceased.  Hlackwater  Fever,  Case  16.  Many  of  the  larger  renal 
tubules  (mostl)-  convoluted  tubules)  and  some  of  the  smaller  contain 
darkly  staining  material,  partially  filling  the  lumen.  This  material  is 
in  part  so  darkly  stained  as  to  look  homogeneous,  but  where  less  dense 
it  can  be  recognised  to  be  made  up  of  irregular  granules  of  varying 
size.  The  epithelium  of  the  renal  tubules,  which  in  this  section  is 
very  faintly  stained,  does  not  present  any  unmistakable  evidence  of 
degeneration.  The  interstitial  tissue  does  not  exhibit  any  marked 
increase  in  amount,  nor  any  cell  infiltration.  Xo  malarial  pigment 
can  be  recognised.  Fixed  in  Flemming’s  solution.  Stained  with  iron 
alum  haematoxylin.  x  160. 
