I2I 
large  darkly  staining  granules  and  masses  composed  of  groups  of 
granules  more  or  less  completely  fused  together.  These  granules 
and  granular  masses  were  accompanied  by  epithelial  cells  lying  free 
in  the  lumen  of  the  tubules,  and  also  by  a  variable  amount  of  lightly 
staining  granular  and  flocculent  material.  The  individual  darkly 
.staining  granules  were  usually  of  large  size,  ranging  from  3/«  to  5/i 
in  diameter,  and  in  addition  collections  of  darkly  staining  granules 
of  much  .smaller  size,  measuring  2n  to  less  than  o’ 5/i  in  diameter, 
were  frequently  met  with  (Figs.  43  and  57).  The  lumen  of  the 
tubules  generally  contained  numerous  epithelial  cells.  Throughout 
the  kidneys  the  epithelial  cells  lining  the  tubules  were  more  or  less 
200  jX 
Oji  120  jJL 
^  kidney  during  experimental  haemoglobinuria. 
®  ml"  ^I’bules  dark  masses  containing 
granules  are  seen.  Ihe  individual  granules  are  small  and  vary  in 
hHthv  ^  Somewhat  scanty.  The  renal  epithelium  is 
no  are  not  dilated.  The  inter.stitial  tissue  shows 
cLillaries  Cells  are  recognisable  in  several  intertubular 
S ineri  fvUh  1  Malpighian  capsule.  Hardened  in  alcohol, 
stained  with  iron  alum  haeniatoxybn.  x  170, 
