Similar  renal  plugs  were  observed  in  cattle  and  dogs  during  rod 
water  due  to  piroplasmosis  (Fig.  52). 
The  kidneys  of  the  rabbit  fourteen  hours  after  the  cessation 
of  haemoglobinuria  were,  however,  in  all  respects  normal,  no  granular 
material  being  present  in  the  tubules  (Figs.  50  and  51). 
OjJ.  UO IX  JOO  jx 
I'lG.  51.  Longitudinal  section  of  medulla  of  kidney  fourteen  hours  after 
experimental  haemoglobinuria.  Rabbit  g,  table  35;^  three  collecting 
tubule.s  are  seen,  also  several  small  tubules.  The  epithelium  is 
everywhere  healthy  in  aspect.  A  small  amount  of  deposit  is  seen  in 
the  lumen  of  some  of  the  tubules,  but  no  darkly-staining  materiah 
There  is  no  c\ilatation  of  the  tubules,  and  the  inter.stitiat  tissue  t.s 
normal  in  a.spect.  Fixed  in  Flemming’.s  solution.  Stained  with  iron 
alum  haematoxylin.  x  153. 
In  the  experiments  upon  rabbits,  already  described  ( 1  ables  35, 
37),  in  which  haemoglobinuria  was  produced  by  the  intravenous 
injection  of  dissolved  haemoglobin,  an  increased  flow  of  urine 
occurred.  Up  to  the  present  we  have  not  obtained  suppression  of 
urine  after  injection.  It  will  be,  however,  of  interest  to  refer  at  this 
point  to  a  group  of  experiments  carried  out  by  different  observers, 
in  which  haemoglobinuria  has  been  followed  b)'  anuria.  In  these 
experiments  haemoglobinuria  was  produced  by  the  injection  of  a 
