Kig.  54.  Section  of  medulla  of  kidney  during  supjrression  of  urine,  eight 
days  after  haemoglobinuria  had  ceased.  Blackwater  Fever,  Case  7a. 
A  collecting  tubule  is  shown  in  transverse  section,  in  the  lumen  of 
which  are  seen  darkly  stained,  two  large  irregular  masses,  and  several 
smaller  collections  of  granules.  The  individual  granules  measure 
from  2/i  to  4^  in  diameter.  Four  free  epithelial  cells  are  also 
present  in  the  lumen  of  the  tubule.  The  cytoplasm  of  the  latter  is 
more  homogeneous  in  aspect  than  that  of  the  epithelial  wall  of  the 
tubule,  which  is  unchanged  in  appearance.  Hardened  in  alcohol. 
Stained  with  iron  alum  haematoxylin.  x  850. 
FtG.  55.  Section  of  cortex  of  kidney  during  suppression  of  luine,  live 
days  after  haemoglobinuria  had  ceased,  lilackwater  Fever,  Case  ii. 
An  asceirding  limb  of  Henle’-s  loop  is  seen  in  transverse  section. 
The  lumen  of  the  tubule  contains  darkly  stained  masses,  composed 
of  partially  coalesced  granules,  the  smallest  of  which  are  about  a/r  in 
diameter.  In  addition  three  free  renal  cells  are  seen  in  the  tubule. 
To  the  right  is  a  portion  of  a  convoluted  tubule,  and  below  and  to 
the  left  a  blood  vessel.  The  renal  epithelium  is  very  granular  in 
aspect.  Hardened  in  alcohol.  .Stained  with  iron  alum  haematoxylin. 
X  850. 
Fig.  56.  Section  of  medulla  of  kidney  during  suppression  of  urine,  live 
days  after  haemoglobinuria  had  ceased.  Blackwater  Fever,  Case  ti. 
A  large  collecting  tubule  is  .shown  in  transverse  section,  containing 
darkly  stained  granules  i/x  to  3/r  in  diameter,  arranged  in  groups  of 
varying  size,  and  accompanied  by  lightly  stained  flocculent  and 
finely  granular  material.  The  epithelial  wall  of  the  tubule  is  unaltered 
in  aspect,  as  is  also  the  interstitial  tissue.  Hardened  in  alcohol. 
Stained  with  iron  alum  haematoxylin.  x  850. 
Fig.  57.  Section  of  cortex  of  kidney,  seven  days  after  haemoglobinuria 
had  ceased.  Blackwater  Fever,  Case  16.  A  renal  tubule,  probably 
an  ascending  limb  of  Henle’s  loop,  is  shown  cut  across  transversely. 
The  wall  of  the  tubule,  which  retains  its  epithelial  lining,  is  faintly 
stained  so  that  its  outlines  are  indistinct.  In  the  lumen  of  the  tubule 
are  numerous  darkly  stained  granules,  varying  in  size  from  less  than 
i/i  to  about  4/i  in  diameter,  in  part  arranged  in  groups.  In  addition 
a  large  amount  of  lightly  tinted  granular  material  is  also  recognisable. 
Fixed  in  Flemming’s  solution.  Stained  with  iron  alum  haematoxylin. 
x  850. 
Fig.  58.  .Section  of  medulla  of  kidney,  seven  days  after  haemoglobinuria  | 
had  ceased.  Blackwater  Fever,  Case  16.  A  collecting  tubule,  lightly  I 
stained,  is  seen  in  transverse  section.  The  lumen  of  the  tubule  is 
filled  with  darkly  stained  granules,  mostly  aiTanged  in  groups.  The 
individual  granules  measure  i/x  to  3/i  in  diameter.  The  epithelial  ] 
lining  of  the  tubule  is  partially  detached.  ITnlike  the  preceding  | 
section,  there  is  very  little  unstained  debris  contained  within  the  I 
lumen  of  the  tubule.  Hardened  in  alcohol.  Stained  with  iron  alum  ' 
haematoxylin.  x  850.  1 
Fig.  5q.  Section  of  cortex  of  kidney  during  experimental  haemoglobinuria.  ^ 
Rabbit  7,  Table  35.  A  renal  tubule  is  shown,  containing  granules 
to  ifi  in  diameter,  which  occupy  a  relatively  small  portion  of  I 
the  lumen  of  the  tubule.  These  granules  are  darkly  stained,  but  I 
slightly  less  so  than  is  represented  in  the  Figure.  No  other  debris  ^ 
i.s  present  in  the  tubule.  The  epithelial  lining  of  the  tubule  wall  i.s 
well  defined,  .some  of  the  divisions  between  the  individual  epithelial 
cells  being  recognisable.  Hardened  in  alcohol.  Stained  with  iron 
alum  haematoxylin.  x  850.  1 
Fig.  fio.  .Section  of  medulla  of  kidney  during  experimental  j 
haemoglobinuria.  Rabbit  7,  Table  35.  A  collecting  tubule  is  shown 
cut  across  longitudinally.  The  lumen  of  the  tubule  is  for  the  most  | 
part  occupied  by  lightly  staining  flocculent  material  containing  a  few  ; 
very  fine  darkly  stained  granules  the  diameter  of  the  largest  of  which  | 
does  not  exceed  The  epithelial  lining  of  the  tubule  is  normal 
in  aspect.  Hardened  in  alcohol.  .Stained  with  iron  alum 
haematoxylin.  x  850.  ^ 
I 
