6Lh  day.  At  6  p.m.  patient’s  oxalated  plasma  was  of  a  dark 
orange  colour  with  a  distinct  reddish  tint.  Oxyhaemoglobin  bands 
were  distinct,  the  blood  plasma  containing  O' 57  per  cent,  of  oxyhaemo¬ 
globin.  No  autolysin  present.  No  malarial  parasites  or  pigmented 
leucocytes  were  found  in  the  blood.  At  10  p.m.  patient's  oxalated 
plasma  was  of  a  dark  orange  colour  with  a  distinct  reddish  tint. 
Oxyhaemoglobin  bands  were  distinct,  the  blood  plasma  containing 
0’4  per  cent,  of  oxyhaemoglobin.  No  autolysin  present  in  the  plasma. 
No  malarial  parasites  or  pigmented  leucocytes  were  found  in  the 
blood. 
/th  day.  At  11-45  patient's  oxalated  plasma  was  light  yellow 
coloured,  with  no  reddish  tint.  Oxyhaemoglobin  bands  were  faint, 
the  blood  plasma  containing  0-8  per  cent,  of  oxyhaemoglobin.  No 
autolysin  was  present  in  the  plasma,  and  no  malarial  parasites  or 
pigmented  leucocytes  wer.e  found  in  the  blood. 
The  following  observations  were  made  at  37°  C.  with  the  patient’s 
red  blood  cells  suspended  in  0'9  per  cent,  sodium  chloride  solution  to 
which  cpiinine  bihydrochloride  had  been  added  :  -  - 
No.  of 
experi¬ 
ment. 
Composition  of  Mixture  of  Red  Blood  Cells  and 
Quinine  Solution. 
Haemolysis. 
2*5  of  %  emulsion  of 
red  blood  cells 
1 
0*9  %  solution  of 
sodium  chloride 
1-92  %  solution  of 
quinine  bihydro- 
diloride 
i 
0*4  c.c. 
2*0  c.c.  1 
01  c.c. 
Complete  in  .1  hour 
z 
0-5  c.c. 
2*4  c.c.  1 
0‘I  c.c. 
Complete  in  i  hour 
0-65  c.c. 
3-0  c.c.  j 
o-i  c.c. 
Complete  in  ij  hours 
4 
0'8  c.c. 
4*6  c.c. 
1 
O'l  c.c. 
Complete  in  2J  hours 
8th  day.  At  10  a.m.  patient’s  oxalated  plasma  was  orange 
coloured.  Oxyhaemoglobin  bands  were  faint,  the  blood  plasma 
containing  0'08  per  cent,  of  oxyhaemoglobin.  On  examination  with 
the  aid  of  the  haemocrit,  the  patient’s  blood  was  found  to  contain 
20  per  cent,  by  volume  of  red  cells.  A  haemoglobinometer  reading  of 
30  divisions  of  Von  Fleischl’s  scale  was  obtained  (equivalent  to  O'og 
per  cent,  of  wet  red  cells).  A  haemocytometer  enumeration  gave  the 
following  figures;— Red  corpuscles,  2,612,500  per  mm.^ ;  leucocytes, 
5,470  per  mm.3  Red  cell  index  =  0-58.  No  autolysin  present.  No 
parasites  and  no  pigmented  leucocytes  were  seen  in  the  blood. 
