Ujl 
jnd  clay.  The  urine  remained  porter  coloured  all  day. 
3rd  day.  This  morning  the  urine  was  light  red.  Later  m  the  day 
it  cleared  up,  becoming  dark  amber  coloured,  sp.  gr.  roi4,  acid.  There 
was  a  slight  deposit  on  centrifugalising,  consisting  of  granular  casts, 
few  red  cells  and  epithelial  cells.  The  supernatant  fluid,  when 
examined  with  the  spectroscope,  gave  no  bands  of  oxyhaemoglobin 
or  methaemoglobin.  There  was  a  slight  whitish  precipitate  on 
acidifying  with  acetic  acid  and  boiling. 
4th  day.  Urine  was  amber  coloured,  sp.gr.  roi6,  no  deposit  on 
centrifugalising,  and  no  precipitate  on  acidifying  and  boiling. 
Blackwater  Fever.  Case  Oa. 
.See  history  of  preceding  attack  (Case  6).  Has  remained  in  good 
health  since  his  last  attack  of  blackwater  fever  about  two  months  ago, 
with  the  e.xception  of  one  attack  of  malaria  which  occurred  about 
three  weeks  ago.  During  the  past  two  months  he  has  only  taken  an 
occasional  ten-gram  dose  of  quinine.  Yesterday  evening  he  did  not 
feel  very  well,  and,  consequently,  took  ten  grains  of  quinine  and  went 
to  bed. 
1st  day.  Patient  got  up  this  morning  feeling  better,  and  took 
another  ten  grains  of  quinine.  Later  in  the  day  he  began  to  feel  very 
ill,  and  had  to  go  to  bed  again.  At  7-30  p.m.  T.  103-4°  F..  At  8  p.m. 
he  passed  blackw^ater.  Vomiting  very  troublesome.  At  1 1  p.m. 
T.  100-2°  F. 
2nd  day.  Condition  unchanged  to-day.  Urine  brownish  coloured. 
3rd  day.  Patient  was  rather  exhausted.  Vomiting  troublesome. 
Skin  and  conjunctivae  of  a  lemon-yellow  colour,  ft  was  impossible 
to  satisfactorily  palpate  the  spleen  owing  to  the  rigidity  with  which 
the  abdominal  walls  were  held.  Urine  of  brow-nish  colour. 
'1'.  98-2°  F. 
4th  day.  Patient  rather  better,  but  vomiting  was  still  severe. 
The  urine  had  almost  completely  cleared  during  the  morning. 
5th  day.  .The  vomiting  had  stopped,  and  the  urine  was  amber 
coloured. 
Condition  of  blood.  3rd  day.  At  4'3'^  p.m.  patient’s  oxalated 
plasma  was  of  a  pale  orange  colour  with  no  red  tint,  containinp-  o-lfi 
per  cent,  of  haemoglobin.  No  autolysin  was  present  in  the  plasma, 
and  no  parasites  or  pigmented  leucocytes  were  found  in  the  blood. 
