iy8  I 
■8th  day.  General  condition  has  remained  good  until  to-day.  [<; 
now  letharg'ic  and  feeble.  Has  occasional  dyspnoea.  Had  Cheyne- 
.Stokes  respiration  for  a  short  time  last  night.  Vomiting  recommenced 
to-day.  Vomited  three  times  this  morning.  In  the  evening  dyspnoea  , 
increasedj  e.specially  after  slight  movement  in  bed,  patient  became 
restless  and  his  extremities  cold.  Slight  anasarca  of  hands  and  face 
A  few  fine  rales  at  lower  borders  of  lungs,  breath  sounds  loud  and  ^ 
harsh  generally.  Total  urine  41  c.cm.  i 
gth  day.  .Slept  last  night  after  administration  of  morphia.  Mucli  1 
inpiroved  again  this  morning.  Total  urine  23  c.cm. 
IC 
loth  day.  Excej.it  for  dysjinoea  is  fairly  comfortalilc.  Died 
suddenly  at  5  ji.m.  from  cardiac  failure.  Total  urine  43  c.cm. 
(] 
Condition  of  blood. —  ist  day,  10  a.m.  Blood  jilasma  of  deep  j, 
orange  colour,  no  distinct  reddish  tint  being  recognisable  with 
certainty ;  contains  074  per  cent,  of  dissolved  haemoglobin ;  no  t 
autolysin  jiresent.  No  malarial  parasites  present  in  blood  smear,  \ 
The  following  observations  were  made  at  37°  C.  with  the  patient's,' 
red  blood  cells  susjiended  in  eg  per  cent,  sodium  chloride  solution  to  ^ 
which  quinine  bihydrochloride  had  been  added  :  1 
No.  of 
experi- 
ment. 
Composition  or  Mi.xtiire  of  Red  Blood  Cem.s  .snd 
Quinine  Solution. 
H.iemolvsii. 
2*5  %  emulsion  of 
red  blood  cells 
0-9  %  solution  of 
sodium  chloride 
1*92  solution  of 
quinine  bihydro¬ 
chloride 
I 
0*5  c.c. 
2*4  c.c. 
O’ I  c.c. 
Complete  in  i  hour. 
2 
0-65  c.c. 
3-0  c.c. 
O’ I  c.c. 
Complete  in  2  houn 
3 
0'8  c.c. 
y6  c.c. 
O’T  c.c. 
Marked  in  3  houri. 
4 
\-o^  c.c. 
4-6  c.c. 
O’ I  c.c. 
Trace  in  3  hours. 
5 
I-.-!  c.c. 
5-6  c.c. 
O’  t  c.c. 
Trace  in  3  hours. 
I. 
t 
