1 
nutolysin  was  present  in  the  plasma,  and  no  parasites  or  pigmented 
leucocytes  were  found  in  the  blood.  The  following  observations 
were  made  at  37°  C.  with  the  patient’s  red  blood  cells  suspended  in 
o'Q  per  cent,  sodium  chloride  solution  to  which  quinine  bihvdrochloride 
had  been  added  : 
C'oMPostTioN’  OK  Mixturk  OF  Rf.d  Rlood  C’f.i.i.s  a\d 
QiTixrbTE  Solution. 
No.  of 
experi- - 
moot. 
2*5  %  emulsion  of  0*9  %  solution  of  1-92  solution  of 
red  blood  cells  sodium  chloride  quinine  bihydro¬ 
chloride 
I  rRcmolvuj. 
I 
0'4  c.c. 
2-0  c.c. 
O*  I 
c.c. 
Complete  at  end  of  i  hours 
2 
0*5  c.c. 
2*4  c.c. 
OM 
c.c. 
Complete  at  end  of  3  hour* 
3 
0-65  c.c. 
3*0  c.c. 
0*1 
c.c. 
Complete  at  end  of  3  hours 
4 
0-8  c.c. 
3'6  c.c. 
0‘I 
c.c. 
Complete  at  end  of  3  hours 
5 
1*05  c.c. 
4-6  c.c. 
O’ I 
c.c. 
.'Mmost  complete  at  end  of 
3  hours 
6 
1--',  c.c. 
3*6  c.c. 
0*1 
c.c. 
Slight  at  end  of  3  hours 
7 
i’5  c.c. 
6'4  c.c. 
o-i 
c.c. 
Slight  at  end  of  3  hours 
8 
17  c.c. 
7*2  c.c. 
O' I 
c.c. 
'Trace  at  end  of  3  hours 
6th  day.  At  lo  a.m.  patient’s  oxalated  plasma  was  of  a  deep 
orange  colour,  with  no  red  tint,  containing  o'O/  per  cent,  of  haemo¬ 
globin  in  solution.  No  parasites  or  pigmented  leucocytes  were  found 
in  blood  smears.  The  following  observations  were  made  at  37°  C. 
with  the  patient's  red  blood  cells  suspended  in  op  per  cent,  sodium 
chloride  solution  to  which  quinine  bihydrochloridc  had  been  added  :  — 
Composition  of  Mixture  of  Rf.d  Blood  Cells  and 
Quinine  Solution. 
No.  of 
experi¬ 
ment. 
2' 5  %  emulsion  of 
red  blood  cells 
0*9  %  solution  of 
sodium  chloride  ' 
1*92  S',',  solution  of 
quinine  bihydro¬ 
chloride 
Haemolysis. 
I 
o*^  c.c. 
2'4  c.c. 
OM  c.c. 
Complete  at  end  of  3  hours 
2 
0-65  c.c. 
3'0  c.c. 
o*r  c.c. 
C'omplete  at  end  of  3  hours 
3 
^  0*8  c.c. 
3-6  c.c. 
0*1  c.c. 
Complete  at  end  of  3  hours 
4 
1*05  c.c. 
4'6  c.c. 
0*1  c.c. 
Slight  at  end  of  3  hours 
1*3  c.c. 
5'6  c.c. 
OM  c.c. 
'Prace  at  end  of  3  hours 
6 
1*5  c.c. 
l-4  c.c. 
OM  c.c. 
Nil  at  end  of  3  h<uirs 
