I 
J.-i5 
Chinsali,  which  has  certainl}.'  been  in  existence  since  1905,  and  which 
normally  takes  its  toll  of  but  two  or  three  per  annum. 
As  will  be  expected,  the  symptoms  vary  with  the  nature  of  the 
infection  :  from  the  acute  febrile  condition  of  a  week  or  two’s  duration 
to  the  emaciated  hairless  skeleton,  which  has  presumably  taken  at 
least  a  year  to  produce.  In  the  absence  of  any  positive  diagnosis 
recovery  may  be  disputed ;  but  certain  owners  are  emphatic  that 
animals  with  a  history  of  exposure,  and  all  clinical  symptoms  of 
trypanosomiasis,  have  recovered,  and  w^e  have  examined  such  without 
seeing  trypanosomes.  Neither  can  the  post-mortem  appearance  be 
regarded  as  constant.  The  enlarged  spleen  and  haemorrhagic  glands 
of  the  acute  case ;  the  oedematous  tissues  and  accumulation  of  fluid 
m  the  body  cavities ;  and  the  dry,  fatless  muscles,  the  pale  tissues 
and  organs  with  slight  oedema  of  the  lymphatic  glands-the  only- 
moisture  present  are  according  to  the  observation  of  ourselves  and 
of  others,  all  met  with. 
hurther  work  on  the  nature  of  the  trypanosomes  encountered  in 
the  territory,  and  their  geographical  distribution,  is  required  before 
the  questions  of  insusceptibility,  immunity  and  recovery  can  be 
logically  discussed. 
Goats  and  Sheep  are  regarded  alike  by  Europeans  and  natives  as 
immune.  On  primd  facie  grounds  the  disease  in  them  is  therefore 
chronic.  We  have  seen  animals  three  and  a  half  months  after  the 
diagnosis  of  the  natural  disease  in  as  good  condition  as  at  first,  and 
not  suspected  of  sickness  by  observant  owners. 
Twenty-three  goats  and  sheep  were  successfully  inoculated  with 
various  strains  ;  the  only  failures,  three,  being  at  Broken  Hill  with 
T.  vivax  (gland  puncture  was  not  resorted  to). 
Speaking  broadly,  trypanosomes  were  generally  visible  in  the 
peripheral  blood,  both  in  naturally  and  experimentally  infected 
animals,  and  being  apparently  m  good  health,  it  appears  to  us  that 
they  may  act  as  reservoirs  par  excellence  for  the  virus,  and  by  trade 
and  movement  may  become  dangerous  potential  disseminators  of  the 
disease. 
In  Dogs  the  disease,  when  fatal,  appears  to  be  somewhat  acute, 
and  accompanied  by  intermittent  fever,  progressive  debility,  opacity 
of  the  cornea,  and  frequently  by  nervous  symptoms.  It  would  seem, 
