528 
the  ears,  etc. ;  it  is  apt  to  be  forgotten  and  taken  irregularly,  and  is 
eventually  given  up.  On  the  other  hand,  I  have  had  no  difficulty  in 
persuading  people  to  take  the  smaller  daily  dose  and  have  seen  no 
bad  effects  from  it.  The  action  of  the  quinine,  of  course,  is  its 
poisonous  effect  on  the  malarial  parasites,  and  the  immature  stages, 
more  especially  that  which  is  injected  from  the  salivary  glands  of 
the  mosquito,  appear  to  be  more  susceptible  than  the  adult  forms, 
which  require  larger  doses. 
I  may  consider  briefly  the  administration  of  quinine  to  different 
sections  of  the  population:  — 
(a)  The  Police 
Here  we  have  to  deal  with  a  disciplined  body,  under  easy 
control,  and  the  problem  is  simple.  With  a  force  of 
1,146  station  officers  and  men  in  igo8  (according  to  the  figures 
supplied)  a  daily  dose  of  five  grains  would  require  4,803  ounces  of 
quinine.  At  a  wholesale  cost  of  is.  an  ounce  this  would  involve  an 
expenditure  of  £2Ap  per  annum  approximately  if  given  to  every 
man— considerably  less  than  it  costs  to  keep  the  men  in  hospital. 
But  it  will  not  be  necessary  to  administer  quinine  universally.  Many 
of  the  stations,  as  shown  in  Table  VIII,  are  free  from  malaria,  so 
that  the  regular  administration  of  quinine  at  those  stations  is  not 
necessary,  unless  for  limited  periods,  in  the  case  of  men  transferred 
from  malarious  localities.  Consequently  the  cost  will  be  considerably 
below  that  stated. 
Here,  again,  a  systematic  method  must  be  adopted.  There 
should  be  a  daily  morning  quinine  parade  at  which  each  man  should 
be  compelled,  unless  exempted  by  the  Medical  Officer,  to  swallow 
five  grains  of  quinine.  This  should  be  done  under  the  personal 
supervision  of  the  sergeant-in-charge,  and  the  District  Inspector 
should  occasionally  himself  superintend.  A  Quinine  Book,  ruled  in 
columns  for  each  day  of  the  month,  should  be  kept,  and  an  entry 
made  opposite  the  name  of  the  constable.  When  not  taken,  a  note 
should  be  made  of  the  reason  for  non-administration. 
A  monthly  return  should  be  sent  in  to  the  Inspector-General 
showing  the  number  of  doses  given,  the  number  of  men  off  duty  from 
malaria,  the  average  daily  sick  in  hospital  from  malaria,  and  the 
proportion  of  daily  sick  from  malaria  to  daily  strength.  This  would 
