EXTRACTS FROM EXCHANGES. 
277 
AMERICAN REVIEW. 
Intravenous Injection of Artificiae Beood-Serum for 
THE Relief of Toxaemia and Extensive Haemorrhages 
\_By Thomas V. Simpson^ V.S.^ Yoj^kton^ N. W. 71 ].—The 
author directs attention to the intravenous or snbcntaneons injec¬ 
tion of saline solution for -relief of toxseinia, due to specific micro- 
organisnis or poisons from other sources, and for combatting ex¬ 
tensive haemorrhage. Best results have been obtained in col¬ 
lapse, due to loss of blood, the artificial serum taking place of 
lost blood and having haemostatic action. In grave septic in¬ 
fection or intoxication it is clearly indicated. When large in¬ 
jection has been given for toxaemia there seems to be only very 
slight improvement for a few minutes ; then there develops a 
strong rapid pulse, rigors, great uneasiness, and the sweat-glands 
and kidneys pour forth their excretions in large quantities. A 
Clydesdale mare, weighing 1300 pounds, gave birth to dead foal. 
In her struggles got her head and feet fast under manger, and 
had been in that position for three or four hours ; quickly got 
on feet and showed fever. I found she had not ejected the 
foetal coverings ; pulse 60, temperature a little above normal. 
Gave her a uterine injection of creolin in solution. AX night 
she was lying down ; pulse and temperature high. As she was 
in o-ood condition I decided to trv venesection and removed 
o * , 
eight quarts, which appeared to give relief, the pulse now being 
quite soft, while before it was hard and full. Next morning 
found her a great deal worse; pulse 100, temperature high. 
Was lying down and showing well-marked symptoms of septic 
metritis. Prognosis doubtful. Then decided to try intravenous 
injection of salt solution, and ordered five gallons of water to be 
boiled. In meantime curetted uterus, after injecting creolin 
solution. Then she ejected all the creolin solution, and I gave 
her an injection of weak iodine solution, which she retained. 
iVt II A. M. injected saline solution into jugular, taking about 
forty-five minutes to do so. In evening looked a good deal 
brighter; temperature not much up, pulse 80; passes clear urine 
three or four times an hour. Gave three more gallons of saline 
fluid intravenously, and clothed heavily to induce perspiration ; 
gave another uterine injection of solution of iodine ; would fre¬ 
quently pass a small quantity of dirty-brown putrid matter from 
uterus. Next day pulse and temperature the same, slight rigors 
and passage of putrid fluid taking place. Then gave seven 
gallons of saline fluid intravenously. Through neglect assistant 
