386 
DAVID S. WHITE. 
The recent researches that have been made in relation to this 
disease, and the knowledge that we now have in reference to its 
toxin, explain the indifferent results that have attended the use of 
medicines. While it is true that certain therapeutic agents will, 
for a time, prevent the spasms that occur in tetanus, they can¬ 
not cure the disease, for they do not neutralize the poison, and 
as soon as the animal emerges from the effect of the drug the 
spasms are as bad as ever; but during the entire period the 
nervous system is irritated by the toxin it is gradually losing its 
vitality, and the animal is approaching death. 
The only forms of treatment that are at all promising in the 
light of our present knowledge of this disease are : (i) The use 
of tetanus antitoxin ; (2) the excision or sterilization of the local 
wound ; (3) complete quietude and rest, thus giving an animal 
an opportunity to conserve its strength to the greatest possible 
degree, and make its conditions most favorable for overcoming 
the action of the toxin. It may be that other means of neutral¬ 
izing the toxin will in time be discovered, or that it may become 
possible to produce the elimination of the toxin from the body, 
but as yet all efforts in this direction, including the use of pur¬ 
gatives, diuretics, and diaphoretics, have signally failed. Our 
greatest hope is in the development of the antitoxic treatment. 
THE TUBERCULIN TEST FOR TUBERCULOSIS IN 
MILCH COWS. 
Bv Prof. David S White, Ohio State University (Veterinary Department). 
A Paper read before the Ohi > State Veterinary Medical Association. 
Heretofore in dealing with such chronic contagions diseases 
in onr domesticated animals as, for instance, glanders in the 
horse and tuberculosis in cattle, we have been considerably 
hampered by not being able at all times to recognize them in 
their latent, hidden forms. All that modern developments have 
given ns in the way of special instruments and mechanical de¬ 
vices to help ns determine the presence of disease in internal 
