458 
E. NOCARD. 
The results are identical when the injection is made with 
the dry antitoxin from Hochst. 
April 28th, at 2.30 p. M., I injected 6 milligrammes of dry 
toxin, under the skin of the neck, to three Danish horses—Nos. 
43,480, 48,993 and 52,663. 
May 4th, at 8 A. M., none of these horses seemed sick; 
brought out of their stalls they were gay, strong and supple in 
their movements. 
At 2 o’clock p. M. nothing was abnormal. 
At 5 o’clock, taken out again. No. 48,993 seemed stiff in his 
neck and loins ; his eye was fixed and prominent; the hostler 
affirmed that he was taken ; it was just six times twenty-four 
hours since he was inoculated. I injected at once in the jugular 
5 grammes of dry serum from Hochst (of December, 1896). 
The two horses, examined carefully, had nothing abnormal. 
May 5th, 6 a. m., the two untreated horses showed no signs 
of tetanus. At 10 o’clock examined again; No. 43,480 was a 
little stiff in its walk. I injected at once, in the jugular, five 
grammes of dry serum from Hochst (of December, 1896), dis¬ 
solved in 45 grammes of sterilized water. 
May 6th, No. 52,663, left as witness^ was taken. 
The 7 th, generalized tetanus in all three ; abdomen 
retracted, neck curved, walking as on posts, still some 
appetite. 
On the 8th and 9th symptoms progressed ; resisting trismus, 
entire impossibility to take food. 
On the loth the three horses were still standing, but in a 
miserable condition. 
At 5 o’clock p. M. No. 43,480 (the one treated) fell—and 
died in the evening. 
No. 52,663 (zmtuess) fell and died May 12th. 
The last died during the night of the 13th. 
* 
* * 
No better results are obtained when the injection of anti¬ 
toxic serum is made twenty-four hours before the appearance of 
the first symptoms. 
