474 
GLANDERS. 
An adhesive form of inflammation is set up in the interior of 
the bursa, destroying the greater part of the secreting surface, 
and in few cases have I ever seen it refill. If it should it only 
calls for a repetition of the operation. 
GLANDERS. 
USE OF MAELEINE IN DOUBTFUL CASES. 
DIRECTIONS OF THE CONSURTING COMMITTEE ON EPIZOOTICS 
IN FRANCE. 
Injections of malleine can, as well as inoculations of suspi¬ 
cious products (discharge or pus), be very advantageously em¬ 
ployed in the diagnosis of suspicious cases of glanders. 
In all the cases where revealing inoculation can be applied 
(donkey, guinea pig, dog), malleine might also be used ; in fact, 
ought to be if it gives the complete reaction (hyperthermy, 
large and painful oedema, prostration, etc.,) the diagnosis, 
revealed by the positive result of the inoculations, will have 
a higher degree of certainty ; and, besides, it is not rare to meet 
with lesions similar to glanders, whose products, inoculated in 
the peritoneum of male guinea pigs, give rise to the formation 
of an orchitis very similar to that of glanders ; then the veteri¬ 
narian might be tempted to advise the slaughter of the sick 
animal, but the absence of all reaction to the injection of mal¬ 
leine will guard him against this error of diagnosis. 
And, again, there are doubtful cases where the revealing in¬ 
oculation cannot be used, no inoculable material (discharge 
or pus) being available. 
It is especially, then, that malleine injections must be used ; 
when it gives rise to an elevation of temperature, in the neigh¬ 
borhood or above two degrees, and at the same time, to a warm, 
painful, lasting large swelling, loss of appetite, chills, prostra¬ 
tion, etc., the veterinarian can affirm that the suspicious indi¬ 
vidual is really affected with glanders and demand the slaughter. 
The suspicious animal once condemned and destroyed, what 
