494 
EXTRACTS FROM EXCHANGES. 
fortnight. The other lingered longer and finally was de¬ 
stroyed. 
Ovariotomy and Vaginal Tumors.— Referring to sug¬ 
gestions made by the author of several cases of vaginal tumors, 
recorded in the Record, viz. : the propriety of performing 
ovariotomy with sluts thus affected, Prof. Hobday of London 
rather endorses the idea and relates three cases where he had 
applied the treatment—that is, performing ovariotomy, and 
according to indications leaving the vaginal tumor alone or in¬ 
terfering with it by extirpation and curettage. In a first suc¬ 
cessful case, the uterine papilloma was removed and did not 
return. In a second the growth was left untouched , the ani¬ 
mal had to be destroyed. In a third case the ulcerating papil¬ 
loma was removed with a curette, had a slight tendency to re¬ 
turn and was curetted a second time, since which the animal is 
well. Ovariotomy had been performed in all three. The in¬ 
dications of this are based upon the fact that during oestrum 
“ the bitch is constantly rubbing her hind parts against various 
objects, the tumors (if present) are more vascular, receive injury 
and bleed freely ; the offensive blood-stained discharge, too, 
is increased in amount and the tumor appears to grow more 
rapidly at these times. By ovariotomy the cause of this is re¬ 
moved.” 
ROUMANIAN REVIEW. 
Some Researches in Urethane.— This preparation 
(ethylic ether of carbamic acid) has been the object of experi¬ 
ments made by Hr. Humibresku, who arrives at the following 
conclusions: (i) In dogs, and according to the dose given it 
produces hypnosis more or less profound and lasting; (2) it 
produces it also by intravenous injections ; (3) the drug has no 
action on circulation, but lowers the temperature, reduces the 
respirations and stimulates urinary secretion ; (4) it has no 
action on the pupil; (5) its action does not last long; (6) it 
does not give rise to any gastro-intestinal irritation in small 
doses, and in hypodermic injections gives rise to subcutaneous 
abscesses and irritates the digestive and respiratory mucous mem¬ 
branes ; in veins, even concentrated solutions produce no bad 
effect; (7) the best way to administer it is per mouth, but when 
given in an intoxication by strychnia, subcutaneous or intra¬ 
venous injections are better; (8) it is the most efficacious 
physiological antidote of strychnia ; large doses will remove 
