INOCULATIONS AGAINST RINDERPEST. 
j place, why did it move at all, and, in the second, why did it not 
follow the laws of gravitation instead of pnrsuing an upward 
^ conrse and terminating fully six inches above the openine of 
! the original wound ? ^ 
INOCULATIONS AGAINST RINDERPEST. 
Through the courtesy of Dr. William Sheppard, of Sheeps- 
head Bay, L. I., we have received a copy of the Umtata (Cape 
Colony) Herald oi Oct. 2, giving an account of the meeting of 
the Rinderpest Commission, at which Dr. Gray, Government 
Veterinary Surgeon, explained the details of inoculations against 
that scourge. Dr. Gray was formerly assistant to Dr. Sheppard, 
and went to South Africa some six or seven years ago. We re¬ 
produce the salient points of his report to the Commission ; 
. s^id that as it took from six to eight weeks to 
fortify animals up to the point of obtaining serum from them 
he had arranged to get a supply from Kimberly sufficient he 
hoped to keep them going in the meantime. He then pro- 
; ceeded to state the method of fortifying animals so that serum 
could be obtained from them, and this process as given in the 
Govepiment Gazette of 24th Sept, is as follows A salted ani¬ 
mal is obtained, either one naturally salted or one which has 
been given the rinderpest after having been slightly immunized. 
As soon as the animal has recovered from the disease, it is in- 
I jected with 100 c.c. of virulent blood. This generally produces 
a febrile reaction. As soon as the reaction is over, 200 c.c. are 
r injected, and the dose is thereafter increased to 500, 1000 
; 2000, 3000 and 4000 c.c. at once, always waiting for the re- 
. action from the last inoculation to subside before administering 
I the blood. Dr. Gray continuing said that from such a salted 
; animal 30 c.c. of defibrinated blood or 20 c.c. of serum was an 
effective dose for cattle in which the first symptoms of disease 
had just appeared, and the best results were always obtained 
when each animal in a herd was inoculated just when the first 
signs of rinderpest were visible. It was, he said, immaterial 
where the injection was made provided it was in a place where 
loose flesh. Great care had to be taken in inoculating 
the animals which were being prepared for the purpose of sup¬ 
plying serum, as the injection of doses up to 3000 c.c. into one 
place was inclined to produce abscess or such-like irritation. 
