630 
INOCULATIONS AGAINST RINDERPEST. 
“ The Chairman then read to the meeting a large portion of a 
report by Drs. Turner and Kolle published in the Government 
Gazette. In the course of this report Drs. Turner ^ and Kolle 
state, that during their investigations, in continuation of Dr. 
Koch’s experiments, they had devoted special attention to the 
possibility of procuring an efficient serum. ' Their experiments 
had been carried on both with defibrinated blood and serum and 
the action of these two fluids they found was precisely similar. 
Serum which is defibrinated blood minus the red corpuscles is 
made by allowing the blood to coagulate and the clot to con¬ 
tract. It can with ordinary care be prepared so that with the 
addition of 0.5 per cent, of phenol it may be bottled and kept 
for a long time. As an illustration of the way in which serum 
may be expected to act in infected herds, they allowed 47 ani¬ 
mals to take the disease spontaneously. The serum was in¬ 
jected at various periods after the commencement of the fever, 
with the following results : 
Day of fever when Inoculated. No. Inoc’d. 
ist day . . • • n 
2d “ ... 4 
3d “ . . • • 7 
4th “ ... >9 
5th “ • 8 
6th “ ... 5 
7th • 2 
9th “ ... I 
47 
No. Alive. 
II 
4 
5 
4 
o 
I 
I 
I 
No. Dead, 
o 
o 
2 
5 
8 
4 
I 
o 
27 20 
“ The serum, or defibrinated blood, can be made to give a long 
immunity if it is used after the animal has become infected, or, 
if the animal be purposely infected after the use of the blood or 
serum. In regard to the qnestion of a process to give a pro¬ 
longed immunity to animals not already infected with rinderpest, 
the report goes on to say that serum and not defibrinated blood 
must be used. The experiments carried out show that it is 
rcessary to insure actual infection. The herd in which sev¬ 
eral cattle have died after serum inoculation has usually been 
found to be in a more satisfactory state than the herd in which 
none have died. The object, therefore, is to insure infection ot 
as severe a character as possible, and at the same time to ad- 
minster the serum in such a dose as to insure the safety o t ie 
animal. This object may be obtained by injecting i c.c. of vir- 
