THE MICROBE OF PLEURO-PNEUMONIA. 
379 
porting great success by the adoption of his methods. We 
begin the publication this month of his scientific contribution 
to veterinary literature upon the subject, for which our readers 
are indebted to Prof. W. L. Williams, whose untiring energy 
has induced him to translate it for the benefit of the profession 
of this country. 
ORIGINAL ARTICLES. 
THE MICROBE OF PLEURO-PNEUMONIA. 
By mm. Nocard and Roux. 
With the collaboration of MM. Borel, Salimbeni and Diijardin-Beaurnetz. 
Translated by A. Liautard. 
(Continued from page 240 .) 
APPENDIX. 
First Experiment.— May i6, 1896, at 8 a. m., a Flemish 
cow, suffering with acute pleiiro-pneumonia, is killed. She had 
been sent to Alfort for clinical studies. At the autopsy are 
found : subacute hepatization of almost the entire right lung, 
the anterior lobe and the superior border only are free from 
disease. No effusion in the pleural sac. Dry pleurisy on the 
whole hepatized surface. An enormous quantity of yellowish 
and limpid serosity fills the perilobular and subpleural lym¬ 
phatic sacs. In some points, the pleura is raised by true lakes 
of serosity; with difficulty 20 c.c. of it are collected pure., and 
kept in 50 sterilized closed glass tubes. 
June 2, two collodion bags are prepared and filled with pep¬ 
tone bouillon inoculated with a trace of the serosity collected 
May 16 (a small drop for 10 c.c. of bouillon). The serosity 
which remained on the glass pipette with which this inocula¬ 
tion was made was inoculated on Agar and in bouillon, these 
inoculated tubes were placed in the thermostat. They remained 
sterile. Both collodion bags, hermetically closed, are placed in 
the peritoneum of two rabbits. These rabbits are killed June 
27 ; they are thin, but still vigorous. The collodion bags are 
