582 
OLOF SCHWARZKOPF. 
ture of glycerine and water of equal parts, which rarely fails to 
assist in periodic evacuation of ingesta. Quite often I have 
emptied the bladder with apparent relief. 
But when we now attempt a treatment of the alarming 
symptoms of distress so commonly exhibited by the animal, the 
deep mental depression, the paralysis of the muscles and the 
complete cessation of peristaltic movement, we fail. As the 
pharynx is early paralyzed, deglutition is difficult, if not impos¬ 
sible, and excludes the application of medicines per os. Thus 
we must rely upon hypodermic medication. To counteract the 
nervous depression veratrine, caifeine, strychnine, spirits of cam¬ 
phor, etc., have been recommended. I have applied them all and 
found that veratrine is the only agent to which the organism 
regularly responds by a profuse perspiration, but from which 
no lasting benefit is visible. To stimulate the peristaltic move¬ 
ments eserine has given me many prompt remits, but in severe 
cases it is absolutely inefficient. Of the more modern methods 
of treatment the venous infusion of the normal salt solution has 
given me promising results. 
Out of three cases so treated two recovered. The solution un¬ 
doubtedly produces a general reviving effect, easily perceptible. 
But a relapse may follow, which leaves the animal in a worse con¬ 
dition, and repeated infusions of such large quantities into the 
jugular vein of cows so diseased are impractical because the 
muscles of the bent neck, if straightened, contract spasmodically, 
preventing the operation. Besides, the cow-stable cannot readily 
be fitted into a laboratory and the preparation of the solution 
and the process of infusion require a cleanliness and an assist¬ 
ance that cannot be had in such surroundings. To overcome 
these difficulties I have tried the hypodermic injection of the ar¬ 
tificial serum of Cheron, which was recommended as a substitute 
for the normal salt-solution as being of more precise action and 
applicable in smaller quantities. Of two cases so treated one 
came to rapid recovery, the other ended in death, which appeared 
to be hastened by the injections. 
This was my experience with the treatment of the disease 
