740 
PROF. LIGNIERES. 
the tissues of the kidneys, it looks as if one had to deal with 
toxaemia. 
After intra-peritoneal inocnlation, the animal may die in 
eight or ten hours. From the sixth hour, the mouse lies on its 
belly, the hind legs apart, and seems to move the hind quarters 
with difficulty. These inoculated mice are sensitive to excita¬ 
tions ; the slightest draft of air, as that made with a rapid shak¬ 
ing of the blade of a knife, is sufficient to promote the evacua¬ 
tion of the bloody urine and sometimes is sufficient to kill it. 
Inoculation in the horse is more interesting ; here is the 
resume of one stallion, quite powerful, 12 years old, belonging 
to the Compagnie Generale des Omnibus. Temperatures taken 
before inoculation : 
Nov. 
Dec.l Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
Dec. 
30 
I i 2 
1 
3 
4 
5 
6 
7 
8 
9 
10 
I' 
12 
Morning 
37° 
37°d37°5 
37°8 
37°2 
36°9 
37 
37°i 
37°4 
37°3 
37°3 
37°i 
36°9 
Evening 
37° 
37°5'37°5 
37°2 
37° 
37° 
37°i 
37°2 
37°4 
37°5 
37°7 
37°7 
36°9 
This animal is in good health and has excellent appetite. 
December 12, 1896, at 4.30 p.m., he received in the vein an 
injection of 300 c.c. of a culture of streptococci obtained July 
13, 1896, in the subarachnoid fluid of a paraplegic horse. 
Temperature after the injection, 37°8 ; 3 p. m., 36°8 ; 9.30 p. m., 
37°5 ; II P.M., 39°o. Immediately after the injection, he had light 
colic which lasted one hour, after which he went eating as usual. 
Dec. 13.—Temperature i a.m., 38^8 ; 4 a.m,, 39°4 ; 6 a.m., 39^3 ; 8 A. 
M., 38°2; ioa.m.,38°6; 12 m., 38^2 ; 2 p.m., 38% ; 4 p.m., 38^6 ; 6 p. 
M., 38°6; 8 P.M., 39°5 ; 10 p.m., 39^8 ; 12 p.m., 39°5. Appetite keeps 
good ; has rested, lying down part of the night. 
Dec. 14.—Temperature 2 a.m., 39^3 ; 4 a.m., 39°3 ; 6 A. m., 39°8 ; 8 
A.M., 39°8 ; 10 A.M., 4o°2 ; 12 m,, 40^3; 2 p.m., 40°; 4 p.m., 40°! ; 6 
P.M., 4o°4 ; 8 P.M., 40°2 ; 10 p.m., 4o°4 ; 12 p.m,, 40°5. Has eaten 
poorly. 
Dec. 15.—Temperature 2 a.m., 40^7 ; 4 a.m., 4o°2 ; 6 a.m., 4o° 4 ; 8 
A.M., 4o°2 ; 12 m., 4 o °6 ; 2 p.m., 40°7 ; 4 p.m., 4 o °6 ; 6 p.m., 4o°6 ; 8 P. 
M., 40°4 ; 10 P.M., 4o°6 ; 12 p.m., 40°3. About same condition, small 
swelling of the genital organs. 
Dec. 16. — Temperature 2 a.m., 40^4 ; 4 a.m., 40°! : 6 a.m., 4o°3 ; 8 a. 
M., 4o°4 ; 10 A.M., 4o°i ; 12 M., 4o°2 ; 2 p.m., 4o°5 ; 4 p.m., 40^2 ; 6 p. 
