PARAPLEGIA IN THE HORSE. 
741 
■ M., 40° ; 8 p.M., 39°8 ; 10 p.m., 39°6 ; 12 p.m., 39°. Mucous membranes 
a little dull, appetite most gone. Laid down at 12 o’clock and got up 
without difficulty. Pulse 88, respiration 24. 
Dec. 17.—Temperature 2 a.m., 39^8 ; 4 a.m., 39^9 ; 6 a.m., 40°: ; 8 a. 
M., 40^5 ; 10 A.M., 40° ; 2 P.M., 40° ; 4 p.m., 39°8 ; 6 p.m., 39*^9 ; 8 p.m., 
39° ; 10 P.M., 39°2 ; 12 p.m., 39*^5. Laid down at ii a.m., did not get up 
all day, ate little. From time to time raised his head and looked towards 
j his loins. Pulse 84, respiration 26. 
1 Dec. 18.—Temperature 2 a.m., 39^1 ; 4 a.m., 39° ; 6 a.m., 38^8 ; 8 A. 
! , M,, 38°8 ; 10 A.M., 39°; 12 M., 38‘’9 ; 2 p.m., 38'’9. All attempts made 
to raise him are useless. He dies at 3.30, paraplegic. 
Post-Mortem ,—Intestines seem normal, as well as liver, 
i spleen, lungs, muscles and nervous substance of the cord. 
Bladder is filled with urine, not bloody but albuminous. Kid- 
^ neys very soft. The inoculated streptococcus is found only in 
the kidneys and the subarachnoid fluid of the spinal cord. 
^ Another horse, given to me by Prof. Nocard, was inoculated 
through the jugular vein with 150 c.c. of the culture of a strep¬ 
tococcus obtained from another paraplegic patient. He seemed 
' to be ailing for several days, but after that everything went nor- 
^ mally, when three weeks after the animal dropped suddenly at 
I five o’clock in the afternoon, while one houi before he appeared 
perfectly well. All attempts to raise him failed ; he presented 
; all the symptoms of a characteristic paraplegia. 
I He died the next day without having bloody urine ; this, 
however, was albuminous. In this case, also, the streptococcus 
was found in the subarachnoid and the cephalo-rachidian fluids. 
Evidently these experiments of inoculation are most inter- 
esting; on one side in the mice we have the frequent presence 
of bloody urine and on the other the paraplegic symptoms end- 
■ ing by death in horses. 
It is true, those last are wanting the symptom of bloody 
urine, but this does not always exist in the natural disease, and 
, perhaps it requires some special conditions to make its appear¬ 
ance. 
- If the bloody urine of mice can be promoted by the strepto- 
Ccoccus of strangles, and also, though with more difficulty, by 
ythe streptococcus pyogenes, experience teaches that the former 
i 
