744 
PROF. LIGNIERES. 
ening the slightest suspicion, without causing any apparent 
trouble ; I have already mentioned the fact of a horse which 
remained in apparent perfect health after having received an 
intravenous injection of streptococcus, and from the kidney of 
which, at the time he was killed, a handsome culture of strep¬ 
tococci was obtained. 
I have succeeded in preserving subarachnoid fluid full of 
streptococci from January 4, 1895, to July, 1896 (say a year and 
a half), and found by intraperitoneal injection of the liquid, to 
young mice, that the vitality and virulency of the microbes re¬ 
main. 
One may easily conceive the presence of some streptococci 
in the nervous centres without necessarily giving rise to trouble ; 
but let one of the predisposing causes occur at a given time, 
then the microbe, which was about being destroyed in time, 
pullulates, throws out its toxins, and then appear the lesions 
and symptoms of the disease. 
These predisposing causes are not always necessary ; indeed, 
it has been observed, though not commonly, that horses not 
plethoric were affected, others drop in the stable, and again 
typical cases have occurred in summer. In my series there was 
a horse which was affected in June, and in which I found strep¬ 
tococci in the subarachnoid fluid. 
At the beginning of this communication, I said that I would 
not stop to consider the theories admitted to this day ; I must, 
however, mention the supposition of Prof. Cadeac tending to 
connect paraplegia with the existence of streptococci in the 
blood of the sick animals. Mr. Cadeac does not explain very 
well his opinion, but it is easy to notice that he is guided by 
observations, especially when he says: “We have, however, 
seen several times in a stable where contagious pneumonia ex¬ 
isted, animals, which did not go out present attacks of pseudo¬ 
paraplegia and of hsemoglobinuria.” 
If, now, my opinion upon the treatment of classic paraplegia 
is desired, I would say: Free bleeding as early as possible; 
bolus of sulfonal, 30 or 40 grammes, and subcutaneous injection 
