266 
G. ED. LEECH. 
was pronounced in the pial-septa. At the chiasm the inner 
sheath of the nerve was markedly infiltrated. The pia-mater 
was infiltrated only in the immediate vicinity of the chiasm ; 
otherwise it was perfectly normal. 
The other optic nerve showed also pronounced round cell 
infiltration of the inner sheath at the chiasm. This cell infil¬ 
tration continued with variable intensity all the way down to 
the second eye. 
Both orbits were normal and there was here no suggestion 
of involvement on the part of nerves, muscles or blood vessels. 
The ciliary nerves whereever met with in the sections were 
perfectly normal. The brain and its membranes were normal. 
Micro-organisms were found in both eyes and also in the optic 
nerves. The organisms had somewhat the appearance of gon¬ 
ococci and in the primarily affected eye was observed to be most 
numerous in the ciliary body, iris and choroid, especially in 
that part of the choroid near the papilla. They were also to 
be seen in the retina, in the papilla and about the central 
vessels. In the optic nerve organisms were found in the nerve 
trunk and in the walls of the smaller blood vessels, which pass 
through the inner sheath of the nerve. No organisms were 
found in the outer sheath of the nerve. The condition was the 
same in both optic nerves and in the chiasm. Some few organ¬ 
isms were found in the pia-mater in the immediate vicinity of 
the chiasm. In the second eye micro-organisms were found to 
be most abundant in the posterior part of the eye, just as was 
the case with the first eye. There were no organisms in the 
orbits. 
It will be remembered that neuritis optica existed for some 
time in the second eye before there was a disturbance of vision. 
Deutschmann thought that the neuritis was produced by the 
chemical and metabolic products that precede the migration of 
the organisms and that it was only where the latter had tra¬ 
versed the optic nerves and passed into the second eye that the 
disease spread with rapidity and with its usual destructiveness. 
He regarded the optic nerves and chiasm as the route followed 
