DOG DISTEMPER. 
267 
by the organisms and believed that the pial sheath of the nerve 
and the nerve trunk were the parts preferably attacked, and he 
concluded by stating his position again with respect to the 
pathogenesis of sympathetic ophthalmia, a position which is 
well known. 
Such a case is of undoubted value, for if a general infection 
can be absolutely excluded we are not far from the solution of 
this problem. The observation, however, is an isolated one, 
and while we cannot but appreciate its value, it will never be 
looked upon as conclusive, so long as the experimental side of 
the question remains so one-sided. 
It may be added that a general infection cannot possibly be 
excluded without a bacteriological examination of the blood and 
other organs, as such general infection, especially with strepto¬ 
cocci, is not infrequent as a terminal event in various chronic 
diseases, including cancer of the stomach. The many negative 
results do not disprove the bacteric origin of sympathetic oph¬ 
thalmia, but before regarding such a theory as proved, the spe¬ 
cific organisms must be identified, and especially should this be 
the case with an infection like sympathetic ophthalmia, -a. dis¬ 
ease the pathogenesis of which really does admit of more than 
one reasonable interpretation. 
DOG DISTEMPER. 
By Coleman Nockolds, M. D., V. S., Grand Rapids, Mich. 
(Concluded from page 187.) 
Pathological Anatomy .—The lesions observed in the res¬ 
piratory type of distemper are due to rhinitis, laryngitis, bron¬ 
chitis, and those changes which are peculiar to the different 
chest affections. The nasal mucous membrane is swollen and 
cedematous ; it is covered with a thick greenish purulent ex¬ 
udate, which is also present on the lining membranes of the 
sinuses of the head. Laryngeal and bronchial mucous mem¬ 
brane is red, tumefied and ecchymotic ; the bronchial tubes are 
filled with a muco-purulent and frothy exudate. The lungs, 
