586 
A. C. HASSLOCH. 
symptoms of the disease, diarrhoea being particularly profuse. 
He was given a bolus of 3 iv as an initial dose, and 3 ii in oat¬ 
meal gruel four times a day. At the end of fourth day, the 
dose was reduced to 3 i; at the sixth day he was discharged 
and has worked ever since. 
EPICARIN (VETERINARY). 
Manufactured by Farben-Fabriken of Elberfeld Co. (Germany.) 
This is a condensation product of a salicylic acid derivative 
and betanaphthol, and occurs in commerce as a reddish-brown 
crystaline powder, permanent in air, of a decidedly.acid reaction, 
soluble in alcohol and ether, but insoluble in water. 
Being an acid, it combines readily with the basic alkalies to 
form soluble neutral salts. Its melting point is 199 0 C. The 
veterinary epicarin is a raw product and but little of the pure 
is obtainable. However, when pure, it occurs as small, color¬ 
less,needle-shaped crystals, imparting.a clear straw color to its al¬ 
coholic solution. Veterinary epicarin is non-toxic to such a de¬ 
gree that dogs treated with it and freely licking themselves 
have developed no untoward symptoms, and it is therefore 
preferable to the more toxic parasiticides and germicides, such 
as carbolic acid, creolin, lysol, creosote, trikresol and others 
which are extensively used in the treatment of mange and other 
skin diseases. Experiments of Dr. Geo. Muller, of Dresden, 
with veterinary epicarin, on the sarcoptes minor of the cat and 
acarus folliculorum of the dog proved conclusively that the 
remedy destroyed these parasites in from 5 to 15 minutes, when 
applied in a 10 per cent, solution, in alcohol, while mixtures of 
the remedy with fat, oils and green soap did not prove destruc¬ 
tive for several hours. Prof. Frick, of Hanover, recommends 
the 10 per cent, solution of epicarin in alcohol as the safest and 
most efficient destroyer of acari and sarcoptes. 
My own experience is that epicarin is not only a most ef¬ 
ficient parasiticide, but also of great utility in the treatment of 
itching skin diseases of horse and dog, giving rapid relief from 
the irritability of the skin, accompanying that common disease 
of the dog, eczema, in its manifold forms. In order to secure 
