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sity of immediate treatment for all those bitten by dogs onl 
suspicions. The experiments carried out with that object b 
MM. Cuitle and Vallee, of the Veterinary School of Toulouse 
gave the following results : u Our researches,” say these autl 
ors, u have according to the indications of Van Gehuchten an 
Nelis, been applied upon the plexiform ganglions of th 
pneutnogastric nerves. After fixation to the sublimate, harder 
ing in a series of alcohol and in acetone, inclusion in paraffine 
the thin sections were colored with polychrom blue of Unn 
and differentiated in the ‘ glycerincethromischung ’ of Griiblei 
In nine dogs dead with rabies, we have found the alterations c 
the nervous cells and of the endothelial envelopes described b 
MM. Van Gehuchten and Nelis; even in the less altered part 
of the ganglion, the envelopes were the seat of a marked leucc 
cytar infiltration. To this date, we have not observed an) 
thing like it in the ganglions of healthy dogs or of those tha 
have died with various diseases. But do those ganglionar 
lesions establish themselves prematurely ? Would they b 
found in dogs killed during the course of the disease? Tha 
was the most important question to solve, as it is specially i 
those conditions that the diagnosis remains uncertain ; it is a 
most always dogs that are killed because they have bitte 
some one and are brought to the veterinarian for post-mortem 
and the researches of Nocard and Roux have proved that th 
saliva is virulent, not only after rabies is confirmed, but 24 an 
48 hours before the apparition of the first symptoms. Wit 
the object of solving this serious question, we have inoculate 
six dogs, taking care to make the infection as natural as pos 
sible. To this effect, each one of these animals had injected i 
the semi-tendinosis muscle half a cc. of an emulsion mad 
with the brain of a dog dead with rage des rues (street rat 
ies) ; these dogs were to be destroyed at various periods of th 
disease. To-day, 63 days after inoculation, three are indemnt 
the three others have become rabid, and more or less soon afte 
the apparition of the first symptoms ; they were destroyed. Th 
results obtained are as follows : Dog No. 1 .—Very old ; dum 
rabies after 17 days of incubation; killed 17 hours after th 
apparition of the first rabid signs and at the very outset of th 
paralysis. At the examination of the plexiform ganglions c 
the pneumogastric, all the cells are healthy ; in few section 
and in very rare places, little centres of pericapsular infiltra 
tions are detected. Dog No. 2 .—Raving rabies after 23 day 
of incubation ; killed after the first rabid signs were observer 
