ANTISEPTIC THERAPEUTICS. 
735 
ANTISEPTIC THERAPEUTICS. 
By J. F. Winchester, D. V. S., Lawrence, Mass. 
Read before the American Veterinary Medical Association, Sept. 6, 1900. 
(Concluded from page 668.) 
In closing- this paper I shall digress from my first statement 
that new material would not be introduced, and will call your 
attention to some facts by Dr. A. W. Balch and Mr. W. R. 
Brinckerhoff, of the Harvard Medical School, relating to a 
u Possible Cause of Azoturia,” and the u Pathology of Azoturia.” 
A possible cause of azoturia. 
A. W. Batch (Laboratory of Pharmacology, Harvard Medical School). 
The similarity between certain of the symptoms existing 
in the disease azoturia and those commonly found in lead poi¬ 
soning seemed to make the chemical examination of urines and 
tissues in these cases desirable. 
Examination of the urines from both azoturia cases and 
normal horses showed the presence of lead in several instances, 
although negative results were also obtained in both the normal 
and pathological cases. Chemical examinations were then 
made of brain, liver, spleen, kidney, and psoas muscle when¬ 
ever possible, in order that the distribution of lead in the system 
might be studied. * 
Organs were taken from normal horses and those in which 
death had followed azoturia, pneumonia and colic. As in the 
urines, lead was found in the tissues of cases other than azotu¬ 
ria, but the amounts were much larger and the lead was much 
more widely distributed in the azoturia cases. 
The quantity found in several of these cases, notably the 
livers, was very large indeed, as shown approximately by the 
final tests employed, while in cases other than azoturia a large 
amount was never found. 
The qualitative results have been placed in tabular form, 
but the quantities could not be expressed, as we have no method 
for accurately determining these small amounts of lead. 
