EXTRACTS FROM EXCHANGES. 
755 
good. During the night between the 5th and 6tli day, there 
was a change noticeable, the temperature raised from 38.4°C to 
40°C, the appetite almost entirely ceased, but in spite of this 
strong reaction, the animal remained strong and lively, the 
urine being of the normal color. On July 22 the temperature 
raised to 4o.7°C, the animal refused to partake of any food, and 
was dull, the urine slightly colored, but the blood contained 
only a few hsematozoons. On the 23d the temperature raised 
to 4i.2°C, the animal extremely depressed, absolutely refusing 
all food. The urine was red and became brown on exposure to 
air ; the examination of the blood proved the presence of 
numerous piriform hsematozoons. The counting of the red 
blood corpuscles, which was undertaken by Nocard, proved at 2 
p. M. 3,200,000, being only about half of the normal number. 
At 6 p.m. there were only 1,100,000. Concluding from other 
test animals which manifested the same symptoms as this, it was 
thought by the members of the commission that the animal 
would die the same night. Unexpectedly the condition re¬ 
mained the same on the 24th. The animal still refusing food, 
was constipated, the muzzle was very dry, the urine darker than 
the day before, and only 370,000 red blood corpuscles were 
found in a cubic millimeter of blood. The blood contained less 
parasites, they were not piriform, but more rounded, while the 
temperature dropped almost 3°C., from 4i.2°C. to 38.3°C. On 
July 25 the animal was considerably better, the temperature 
being 38.4°C., the muzzle was fresh, the animal drank, and 
searched for food. The animal seemed to be on the road to 
recovery. As the natural disease which causes immense losses 
in Argentina and also in the United States, does not in every 
case terminate fatally, the recovery of the test animal should 
not be surprising. But the greatest importance is, that the ex¬ 
periments proved without doubt the absolute effect of the inocu¬ 
lation discovered by Ligniere. The two inoculated animals 
were not in the slightest degree affected, while the control 
animal suffered from a severe attack, so much so that a fatal 
termination was expected. In a practical way these experi¬ 
ments were very satisfactory. Now, we are anxious to see Mr. 
Ligniere’s publications in regard to the procedures of the inocu¬ 
lations, and, furthermore, the preparation of the immunizing 
serum and how long the inoculated animals remain immune. 
The Use of Maelein in the Diagnosis of Glanders 
[Dr. Borella Alete \.—During the autopsy of a horse which died 
from colic, lesions on various parts were noticed, similar to the 
