28 
H. E. TITUS. 
4 minutes. Nervousness and muscular trembling with depression. 
5 minutes. Salivation and muscular trembling ; animal uneasy and 
walking around in the box. Successive fluid evacuations—eight in ten 
minutes ; intestinal murmurs very loud. 
io minutes. Dog down and body-surface cold ; pupil of eye much 
contracted. 
45 minutes. All symptoms subsided, and the dog was able to run 
about ; no local inflammation at point of injection. 
VII. —EQUINE. 
This was a gray mare in good condition, weighing eleven 
hundred pounds. 
Administered fifty milligrammes subcutaneously. 
Normal pulse, 42 ; temperature, 99 ; respiration, 17. 
3 y 2 minutes. Salivation and borborygmi very loud. 
8 minutes. Animal shows evidence of abdominal pain by uneasi¬ 
ness. 
10 minutes. Fluid evacuation. 
12 minutes. Fluid evacuation ; salivation by this time is profuse. 
15 minutes. Pulse, 48; temperature, 99.4; respiration, 25; body- 
surface quite warm, but thermometer shows no appreciable rise ; faecal 
passage. 
20 minutes. Pulse, 43 ; temperature, 99.4; respiration, 23 ; faecal 
passage and profuse sweating. 
25 minutes. Evacuation, muscular trembling and respiration very 
labored ; animal showed signs of being very weak ; the body at this 
time is covered with cold sweat. 
30 minutes. Animal began to recover from the effects of the areco- 
line. 
1 hour and 15 minutes. All symptoms had passed away with the 
exception of weakness. 
VIII. —EQUINE. 
This was a bay mare, eight years old, weighing thirteen 
hundred pounds, that was taken sick with flatulent colic. 
Being very tympanitic, she was first punctured with the 
trocar. 
Administered thirty-five milligrammes subcutaneously. 
4 minutes. Uneasiness, intestinal murmurs, and salivation. 
15 minutes. Fluid evacuation, with much flatus. 
1 hour and 30 minutes. Animal was out of danger. No inflamma¬ 
tion at point of injection. 
IX.—EQUINE. 
This was a fourteen-hundred-pound black gelding that de¬ 
veloped acute laininitis. 
Administered thirty milligrammes subcutaneously. 
5 minutes. Salivation and borborygmi. 
16 minutes. Evacuation. 
1 hour. Administered subcutaneously thirty milligrammes of areco- 
