STREPTOCOCCI IN COMPARATIVE PATHOLOGY. 
695 
Its apparent importance warrants the introduction of a summary 
of the observations and results then obtained. 
The lesions were, within certain limits, uniform in all of the 
affected animals. Usually but one foot or leg was attacked, 
although there were numerous exceptions reported. The first 
symptom noticed was a swelling, which usually appeared in the 
lower part of the leg, most often in the pastern. In some ani¬ 
mals it was said that the swelling was restricted to a small area, 
but often it extended up the leg to and even above the knee or 
the hock joint. There was evidence of pain. As the inflamma¬ 
tory process continued, the subcutaneous tissue became indu¬ 
rated, the skin thick and dry, and eventually it would crack, 
usually, but not always, below the dew claws, and a thick 
creamy pus would be discharged. After discharging, the swell¬ 
ing subsided and the normal condition was rapidly restored. 
The time necessary for the suppurative process and recovery to 
take place varied in different animals, but as a rule from ten to 
fifteen days were required. The exceptions were largely in those 
cases where the inflammatory process extended down to the 
coronary cushion. In these there was more or less slouo-hino- 
of the hoof and it was in these cases that the disease appeared 
in its most serious form. So far as I have learned all of the 
affected animals eventually recovered. A personal examination 
was made of five cases, in two herds, which were on adjoining farms. 
The notes on four of these cases are appended. 
Case No. i. A cow", 7 to 8 years old. The trouble was in the right 
hind foot. She had recovered from a severe attack in the right fore foot. 
There was still some swelling in the hind leg and the skin and subcu¬ 
taneous tissue above the heel were much thickened. There were two 
cracks below the dew claws, from which, the owner said, there had been 
a profuse discharge. At this time pus could not be obtained. Several 
small pieces of the infiltrated tissue were secured. From some of these 
agar tubes were inoculated at the time and the others were placed in 
sterile tubes and brought to the laboratory for further examination. 
Case No. 2. This was in a cow, about six years old. The left fore 
leg was just beginning to swell. There was evidence of pain and the 
skin from the hoof to the knee was sensitive to the touch, and the skin 
was appreciably reddened. The temperature was normal, but there was 
indifference to food. This case was treated locally by Dr. Law r , with 
recover without suppuration. 
