STREPTOCOCCI IN COMPARATIVE PATHOLOGY. 
697 
ioth and 12th days suppuration was evident. The abscesses 
were not opened, but a few days later they broke just under the 
dew-claws, near the place of inoculation, and discharged a con¬ 
siderable quantity of cream-colored pus, after which complete 
recovery soon followed. The streptococcus was obtained in 
pure culture from each of these cases. 
A third cow was inoculated with a pure bouillon culture of 
the streptococcus 24 hours old obtained from case No. 4. The 
inoculation was made by scraping the skin on the right fore foot 
just above the hoof, and after removing the epidermis the cul¬ 
ture was rubbed on the raw surface. Swelling began in three 
days and the symptoms already described followed in regular 
order. A subcutaneous abscess formed and on the 14th day it 
discharged. The streptococcus was obtained in pure culture 
from the bottom of the freshly discharged abscess. Recovery 
followed. 
Rabbits inoculated with pure culture of the streptococcus 
succumbed in from 36 to 48 hours to a septicaemia. Guinea- 
pigs were not affected unless injected with very large doses into 
the abdominal cavity. A careful study of these eases showed 
that while the manifestations of the trouble might warrant in a 
few cases the designation of foot-rot, and certain others that of 
erysipelas, the real trouble was simply an inflammatory process 
usually leading to suppuration. The fact that a considerable 
number of animals were similarly infected caused the serious 
apprehension concerning its nature while a single case would 
doubtless have received little if any attention. 
Klein * found streptococci to be quite numerous in the 
lesions of the disease described by him as cow scarlatina, or the 
Hendon cow disease. In another outbreak of an apparently 
infectious disease among cattle which manifested itself by an 
ulcerating process on the teats and udders other streptococci 
were found one of which he considered as “ standing in some 
necessary relation to the disease.” 
(To be continued .) 
* Loc. cit. 
