780 
VERANUS A. MOORE. 
discovered in the uncontaminated lesions. Further examinations 
which were made during the year just closed have given differ¬ 
ent results. During this time ten cases have received such an 
examination. In these, streptococci appeared in pure culture 
twice, associated with micrococci three times and in five other 
cases micrococci (staphylococci) appeared apparently in pure 
culture. Thus in a total of fourteen cases streptococci have 
been isolated in pure culture six times, found in impure cul¬ 
tures three times, and in five cases they were not discovered. 
The streptococci themselves exhibited a few morphologic 
differences. One of them which appeared in pure culture 
originally consisted of exceedingly long chains which grew in 
flocculi in bouillon leaving the liquid clear. In all of the other 
cultures they grew in short chains, imparting a uniform cloudi¬ 
ness to the liquid. 
x\s a rule the streptococci isolated from these affections were 
not pathogenic for experimental animals. One culture, how¬ 
ever, destroyed rabbits and guinea-pigs when first isolated, but 
it soon lost its virulence in sub-cultures. 
In a few cases of the affected withers the lesion consisted in 
a thickened, firm, indurated tissue, rather than the usual cen¬ 
tral abscess. In the most marked of these indurated cases a 
micrococcus (staphylococcus) was the only organism found. In 
most cases, where an abscess had not discharged, and from 
which uncontaminated pus was secured, streptococci were pres¬ 
ent. Whether or not, streptococci tend in the horse to cause a 
moie rapid suppuration than the micrococci can not from the 
history of the cases in question, be determined. It is not posi¬ 
tively determined whether the two distinct varieties of lesions 
observed, viz., the suppurating and the indurated, are different 
types of disease or different stages in the same disease process. 
It is interesting to note, however, that in the few cases exam¬ 
ined streptococci were usually associated with the suppurating 
processes and micrococci (staphylococci) with the indurated 
conditions. A long list of carefully studied cases will have to 
be recorded before such a differentiation in the bacterial con- 
